U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Galm galactose mutarotase [ Mus musculus (house mouse) ]

Gene ID: 319625, updated on 26-Sep-2022

Summary

Official Symbol
Galmprovided by MGI
Official Full Name
galactose mutarotaseprovided by MGI
Primary source
MGI:MGI:2442420
See related
Ensembl:ENSMUSG00000035473 AllianceGenome:MGI:2442420
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
A530057M15Rik
Summary
Predicted to enable aldose 1-epimerase activity. Predicted to be involved in galactose catabolic process via UDP-galactose and glucose metabolic process. Predicted to act upstream of or within carbohydrate metabolic process. Predicted to be located in cytoplasm. Is expressed in several structures, including alimentary system; liver; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in galactosemia. Orthologous to human GALM (galactose mutarotase). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in kidney adult (RPKM 44.1), liver adult (RPKM 34.5) and 20 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Galm in Genome Data Viewer
Location:
17; 17 E3
Exon count:
8
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (80434886..80492461)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (80127458..80185032)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 41626 Neighboring gene predicted gene, 23125 Neighboring gene microRNA 12189 Neighboring gene serine and arginine-rich splicing factor 7

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables aldose 1-epimerase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables aldose 1-epimerase activity ISO
Inferred from Sequence Orthology
more info
PubMed 
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
 
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
 
enables isomerase activity IEA
Inferred from Electronic Annotation
more info
 
NOT enables protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within carbohydrate metabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in galactose catabolic process via UDP-galactose IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in galactose catabolic process via UDP-galactose ISO
Inferred from Sequence Orthology
more info
PubMed 
involved_in galactose metabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in glucose metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in glucose metabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in hexose metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
galactose mutarotase
Names
aldose 1-epimerase
NP_795937.1
XP_006524453.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_176963.4NP_795937.1  galactose mutarotase

    See identical proteins and their annotated locations for NP_795937.1

    Status: PROVISIONAL

    Source sequence(s)
    AC140361
    Consensus CDS
    CCDS28987.1
    UniProtKB/Swiss-Prot
    Q8K157
    Related
    ENSMUSP00000040580.5, ENSMUST00000039205.11
    Conserved Domains (1) summary
    cd09019
    Location:21339
    galactose_mutarotase_like; galactose mutarotase_like

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    80434886..80492461
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006524390.5XP_006524453.1  galactose mutarotase isoform X1

    Conserved Domains (1) summary
    cd09019
    Location:21211
    galactose_mutarotase_like; galactose mutarotase_like