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Dcp1b decapping mRNA 1B [ Mus musculus (house mouse) ]

Gene ID: 319618, updated on 8-Dec-2022

Summary

Official Symbol
Dcp1bprovided by MGI
Official Full Name
decapping mRNA 1Bprovided by MGI
Primary source
MGI:MGI:2442404
See related
Ensembl:ENSMUSG00000041477 AllianceGenome:MGI:2442404
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
B930050E02Rik
Summary
Predicted to enable mRNA binding activity. Involved in cellular response to interleukin-17; protein localization to P-body; and protein localization to nucleus. Located in P-body. Is expressed in embryo. Orthologous to human DCP1B (decapping mRNA 1B). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 25.1), thymus adult (RPKM 8.1) and 25 other tissues See more
Orthologs
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Genomic context

See Dcp1b in Genome Data Viewer
Location:
6; 6 F1
Exon count:
10
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (119152214..119198575)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (119175253..119221614)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene calcium channel, voltage-dependent, L type, alpha 1C subunit Neighboring gene predicted gene, 53338 Neighboring gene predicted gene, 50599 Neighboring gene calcium channel, voltage-dependent, alpha 2/delta subunit 4 Neighboring gene predicted gene, 52874 Neighboring gene leucine-rich repeats and transmembrane domains 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables enzyme activator activity IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
is_active_in P-body IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in P-body IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
mRNA-decapping enzyme 1B
Names
DCP1 decapping enzyme homolog B
NP_001028551.2
XP_006506301.1
XP_017177110.1
XP_017177111.1
XP_030111300.1
XP_030111301.1
XP_030111303.1
XP_036022105.1
XP_036022106.1
XP_036022107.1
XP_036022108.1
XP_036022109.1
XP_036022110.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033379.3NP_001028551.2  mRNA-decapping enzyme 1B

    See identical proteins and their annotated locations for NP_001028551.2

    Status: VALIDATED

    Source sequence(s)
    AC126453, AK047334, AK049193, AK053525
    Consensus CDS
    CCDS39610.1
    UniProtKB/TrEMBL
    B9EIX0
    Related
    ENSMUSP00000108397.3, ENSMUST00000112777.9
    Conserved Domains (2) summary
    cd09804
    Location:16131
    Dcp1; mRNA decapping enzyme 1 (Dcp1)
    pfam16741
    Location:536575
    mRNA_decap_C; mRNA-decapping enzyme C-terminus

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    119152214..119198575
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006506238.4XP_006506301.1  mRNA-decapping enzyme 1B isoform X1

    Conserved Domains (2) summary
    cd09804
    Location:16131
    Dcp1; mRNA decapping enzyme 1 (Dcp1)
    pfam16741
    Location:559598
    mRNA_decap_C; mRNA-decapping enzyme C-terminus
  2. XM_030255443.1XP_030111303.1  mRNA-decapping enzyme 1B isoform X5

    Conserved Domains (1) summary
    pfam16741
    Location:375414
    mRNA_decap_C; mRNA-decapping enzyme C-terminus
  3. XM_030255440.1XP_030111300.1  mRNA-decapping enzyme 1B isoform X4

    Conserved Domains (1) summary
    pfam16741
    Location:398437
    mRNA_decap_C; mRNA-decapping enzyme C-terminus
  4. XM_017321622.2XP_017177111.1  mRNA-decapping enzyme 1B isoform X5

    Conserved Domains (1) summary
    pfam16741
    Location:375414
    mRNA_decap_C; mRNA-decapping enzyme C-terminus
  5. XM_036166216.1XP_036022109.1  mRNA-decapping enzyme 1B isoform X5

    Conserved Domains (1) summary
    pfam16741
    Location:375414
    mRNA_decap_C; mRNA-decapping enzyme C-terminus
  6. XM_030255441.1XP_030111301.1  mRNA-decapping enzyme 1B isoform X4

    Conserved Domains (1) summary
    pfam16741
    Location:398437
    mRNA_decap_C; mRNA-decapping enzyme C-terminus
  7. XM_036166215.1XP_036022108.1  mRNA-decapping enzyme 1B isoform X5

    Conserved Domains (1) summary
    pfam16741
    Location:375414
    mRNA_decap_C; mRNA-decapping enzyme C-terminus
  8. XM_036166212.1XP_036022105.1  mRNA-decapping enzyme 1B isoform X2

    Conserved Domains (1) summary
    pfam16741
    Location:433472
    mRNA_decap_C; mRNA-decapping enzyme C-terminus
  9. XM_036166213.1XP_036022106.1  mRNA-decapping enzyme 1B isoform X3

    Conserved Domains (1) summary
    pfam16741
    Location:410449
    mRNA_decap_C; mRNA-decapping enzyme C-terminus
  10. XM_036166217.1XP_036022110.1  mRNA-decapping enzyme 1B isoform X5

    Conserved Domains (1) summary
    pfam16741
    Location:375414
    mRNA_decap_C; mRNA-decapping enzyme C-terminus
  11. XM_017321621.3XP_017177110.1  mRNA-decapping enzyme 1B isoform X2

    Conserved Domains (1) summary
    pfam16741
    Location:433472
    mRNA_decap_C; mRNA-decapping enzyme C-terminus
  12. XM_036166214.1XP_036022107.1  mRNA-decapping enzyme 1B isoform X3

    Conserved Domains (1) summary
    pfam16741
    Location:410449
    mRNA_decap_C; mRNA-decapping enzyme C-terminus