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alpha-Man-Ia alpha-Mannosidase class I a [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31957, updated on 19-Aug-2018

Summary

Official Symbol
alpha-Man-Iaprovided by FlyBase
Official Full Name
alpha-Mannosidase class I aprovided by FlyBase
Primary source
FLYBASE:FBgn0259170
Locus tag
Dmel_CG42275
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
a-Man-Ia; alpha-Man-I; alpha-Man-l; CG17809; CG18799; CG32682; CG32684; CG42275; DM-GI; dManI; dMas-1; Dmel\CG42275; MA12; Man'ase; MAN-1; ManI; mas-1; mas1
Old locus tag
Dmel_CG32682; Dmel_CG32684

Genomic context

See alpha-Man-Ia in Genome Data Viewer
Location:
9B6-9B7; 1-31 cM
Exon count:
11
Annotation release Status Assembly Chr Location
Release 6.13 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (10266792..10325958, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (10160825..10219991, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Hyperkinetic Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene GIP-like

Genomic regions, transcripts, and products

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

mobile_element

  • Loc: c10276449-10267358 mobile_element_type = transposon:roo{}96

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
calcium ion binding IEA
Inferred from Electronic Annotation
more info
 
mannosyl-oligosaccharide 1,2-alpha-mannosidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mannosyl-oligosaccharide 1,2-alpha-mannosidase activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
N-glycan processing IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
determination of adult lifespan IMP
Inferred from Mutant Phenotype
more info
PubMed 
encapsulation of foreign target IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to anesthetic IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
Golgi membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
endomembrane system HDA PubMed 
endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
alpha-Mannosidase class I a
Names
CG42275-PH
CG42275-PI
CG42275-PJ
CG42275-PK
CG42275-PL
CG42275-PM
CG42275-PN
CG42275-PO
CG42275-PP
alpha 1,2 mannosidase
alpha mannosidase I
alpha-1,2-mannosidase I
alpha-D-mannosidase
alpha-Man-Ia-PH
alpha-Man-Ia-PI
alpha-Man-Ia-PJ
alpha-Man-Ia-PK
alpha-Man-Ia-PL
alpha-Man-Ia-PM
alpha-Man-Ia-PN
alpha-Man-Ia-PO
alpha-Man-Ia-PP
alpha-mannosidase
mannosidase 1
NP_001259402.1
NP_511105.2
NP_727407.1
NP_727408.2
NP_996395.1
NP_996396.1
NP_996397.1
NP_996398.1
NP_996399.1

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    10266792..10325958 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_167223.3NP_727407.1  alpha-Mannosidase class I a, isoform J [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_727407.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P53624
    Related
    FBpp0289738.1, FBtr0300511
    Conserved Domains (1) summary
    cl04955
    Location:198647
    LanC_like; Cyclases involved in the biosynthesis of lantibiotics, and similar proteins
  2. NM_078550.4NP_511105.2  alpha-Mannosidase class I a, isoform K [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_511105.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P53624
    Related
    FBpp0289739.1, FBtr0300512
    Conserved Domains (2) summary
    pfam01532
    Location:183623
    Glyco_hydro_47; Glycosyl hydrolase family 47
    pfam05223
    Location:78143
    MecA_N; NTF2-like N-terminal transpeptidase domain
  3. NM_206676.3NP_996399.1  alpha-Mannosidase class I a, isoform L [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_996399.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P53624
    Related
    FBpp0289740.1, FBtr0300513
    Conserved Domains (1) summary
    cl04955
    Location:198647
    LanC_like; Cyclases involved in the biosynthesis of lantibiotics, and similar proteins
  4. NM_206673.3NP_996396.1  alpha-Mannosidase class I a, isoform O [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_996396.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P53624
    Related
    FBpp0289743.1, FBtr0300516
    Conserved Domains (1) summary
    cl04955
    Location:198647
    LanC_like; Cyclases involved in the biosynthesis of lantibiotics, and similar proteins
  5. NM_206674.3NP_996397.1  alpha-Mannosidase class I a, isoform N [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_996397.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P53624
    Related
    FBpp0289742.1, FBtr0300515
    Conserved Domains (1) summary
    cl04955
    Location:198647
    LanC_like; Cyclases involved in the biosynthesis of lantibiotics, and similar proteins
  6. NM_206675.3NP_996398.1  alpha-Mannosidase class I a, isoform M [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_996398.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P53624
    Related
    FBpp0289741.1, FBtr0300514
    Conserved Domains (1) summary
    cl04955
    Location:198647
    LanC_like; Cyclases involved in the biosynthesis of lantibiotics, and similar proteins
  7. NM_167224.3NP_727408.2  alpha-Mannosidase class I a, isoform I [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_727408.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8IRL4
    Related
    FBpp0288908.1, FBtr0299633
    Conserved Domains (1) summary
    pfam01532
    Location:224664
    Glyco_hydro_47; Glycosyl hydrolase family 47
  8. NM_206672.3NP_996395.1  alpha-Mannosidase class I a, isoform H [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_996395.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P53624
    Related
    FBpp0288907.1, FBtr0299632
    Conserved Domains (1) summary
    cl04955
    Location:198647
    LanC_like; Cyclases involved in the biosynthesis of lantibiotics, and similar proteins
  9. NM_001272473.2NP_001259402.1  alpha-Mannosidase class I a, isoform P [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259402.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P53624
    Related
    FBpp0304147.1, FBtr0331759
    Conserved Domains (2) summary
    pfam01532
    Location:183623
    Glyco_hydro_47; Glycosyl hydrolase family 47
    pfam05223
    Location:78143
    MecA_N; NTF2-like N-terminal transpeptidase domain
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