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Idi1 isopentenyl-diphosphate delta isomerase [ Mus musculus (house mouse) ]

Gene ID: 319554, updated on 26-Sep-2022

Summary

Official Symbol
Idi1provided by MGI
Official Full Name
isopentenyl-diphosphate delta isomeraseprovided by MGI
Primary source
MGI:MGI:2442264
See related
Ensembl:ENSMUSG00000058258 AllianceGenome:MGI:2442264
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
IPPI1; 4832416K17Rik
Summary
Predicted to enable isopentenyl-diphosphate delta-isomerase activity; magnesium ion binding activity; and manganese ion binding activity. Acts upstream of or within response to stilbenoid. Located in mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human IDI1 (isopentenyl-diphosphate delta isomerase 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in liver E14 (RPKM 38.1), liver E18 (RPKM 34.3) and 27 other tissues See more
Orthologs
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Genomic context

See Idi1 in Genome Data Viewer
Location:
13; 13 A1
Exon count:
5
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (8935642..8942432)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (8885606..8892396)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene adenosine deaminase, RNA-specific, B2 Neighboring gene WD repeat domain 37 Neighboring gene ribosomal protein L10A, pseudogene 2 Neighboring gene predicted gene, 25274 Neighboring gene isopentenyl-diphosphate delta isomerase 2 like

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 
  • Endonuclease-mediated (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC8139, MGC118013

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables isopentenyl-diphosphate delta-isomerase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables isopentenyl-diphosphate delta-isomerase activity ISO
Inferred from Sequence Orthology
more info
 
enables magnesium ion binding ISO
Inferred from Sequence Orthology
more info
 
enables manganese ion binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in isopentenyl diphosphate biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in isoprenoid biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
involved_in response to stilbenoid IEP
Inferred from Expression Pattern
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in mitochondrion HDA PubMed 
located_in peroxisome ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
isopentenyl-diphosphate Delta-isomerase 1
Names
IPP isomerase 1
isopentenyl pyrophosphate isomerase 1
NP_663335.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_145360.2NP_663335.2  isopentenyl-diphosphate Delta-isomerase 1

    See identical proteins and their annotated locations for NP_663335.2

    Status: VALIDATED

    Source sequence(s)
    AC124732, AK160832, BE953932
    Consensus CDS
    CCDS26233.2
    UniProtKB/Swiss-Prot
    P58044
    UniProtKB/TrEMBL
    G3XA48
    Related
    ENSMUSP00000132780.3, ENSMUST00000169314.9
    Conserved Domains (2) summary
    COG1443
    Location:75278
    Idi; Isopentenyldiphosphate isomerase [Lipid transport and metabolism]
    cl00447
    Location:77283
    Nudix_Hydrolase; Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+ ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    8935642..8942432
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)