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Pced1a PC-esterase domain containing 1A [ Mus musculus (house mouse) ]

Gene ID: 319513, updated on 30-Apr-2024

Summary

Official Symbol
Pced1aprovided by MGI
Official Full Name
PC-esterase domain containing 1Aprovided by MGI
Primary source
MGI:MGI:2442177
See related
Ensembl:ENSMUSG00000037773 AllianceGenome:MGI:2442177
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Fam113a; A930025D01Rik
Summary
Orthologous to human PCED1A (PC-esterase domain containing 1A). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in ovary adult (RPKM 12.2), limb E14.5 (RPKM 11.2) and 28 other tissues See more
Orthologs
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Genomic context

See Pced1a in Genome Data Viewer
Location:
2 F1; 2 63.22 cM
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (130259603..130266692, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (130417683..130424641, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1700020A23 gene Neighboring gene transmembrane 239 Neighboring gene STARR-positive B cell enhancer ABC_E11708 Neighboring gene VSP16 CORVET/HOPS core subunit Neighboring gene predicted gene, 52562 Neighboring gene protein tyrosine phosphatase receptor type A Neighboring gene VISTA enhancer mm1313 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:130358070-130358271 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:130366029-130366233 Neighboring gene RIKEN cDNA 4930473A02 gene Neighboring gene STARR-positive B cell enhancer ABC_E7863

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

General protein information

Preferred Names
PC-esterase domain-containing protein 1A
Names
family with sequence similarity 113, member A
protein FAM113A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001114541.2NP_001108013.1  PC-esterase domain-containing protein 1A

    See identical proteins and their annotated locations for NP_001108013.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks a segment in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    BX890605
    Consensus CDS
    CCDS50711.1
    UniProtKB/Swiss-Prot
    A2BI89, Q6P1Z5
    Related
    ENSMUSP00000105906.2, ENSMUST00000110277.2
    Conserved Domains (1) summary
    cd01842
    Location:34266
    SGNH_hydrolase_like_5; SGNH_hydrolase subfamily. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site ...
  2. NM_178762.5NP_848877.2  PC-esterase domain-containing protein 1A

    See identical proteins and their annotated locations for NP_848877.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer transcript. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    BX890605
    Consensus CDS
    CCDS50711.1
    UniProtKB/Swiss-Prot
    A2BI89, Q6P1Z5
    Related
    ENSMUSP00000087009.5, ENSMUST00000089581.11
    Conserved Domains (1) summary
    cd01842
    Location:34266
    SGNH_hydrolase_like_5; SGNH_hydrolase subfamily. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    130259603..130266692 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036162287.1XP_036018180.1  PC-esterase domain-containing protein 1A isoform X2

    Conserved Domains (1) summary
    cl01053
    Location:34266
    SGNH_hydrolase; or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the typical ...
  2. XM_036162290.1XP_036018183.1  PC-esterase domain-containing protein 1A isoform X5

    Conserved Domains (1) summary
    cl01053
    Location:34266
    SGNH_hydrolase; or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the typical ...
  3. XM_036162288.1XP_036018181.1  PC-esterase domain-containing protein 1A isoform X3

    Conserved Domains (1) summary
    cl01053
    Location:34266
    SGNH_hydrolase; or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the typical ...
  4. XM_036162289.1XP_036018182.1  PC-esterase domain-containing protein 1A isoform X4

    UniProtKB/TrEMBL
    Q8BFT7, Q8BUE8, Q8BXP0
    Conserved Domains (1) summary
    cl01053
    Location:1113
    SGNH_hydrolase; or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the typical ...
  5. XM_017318973.2XP_017174462.1  PC-esterase domain-containing protein 1A isoform X1

    UniProtKB/Swiss-Prot
    A2BI89, Q6P1Z5
    Conserved Domains (1) summary
    cd01842
    Location:34266
    SGNH_hydrolase_like_5; SGNH_hydrolase subfamily. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site ...