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Pced1a PC-esterase domain containing 1A [ Mus musculus (house mouse) ]

Gene ID: 319513, updated on 26-Sep-2022

Summary

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Official Symbol
Pced1aprovided by MGI
Official Full Name
PC-esterase domain containing 1Aprovided by MGI
Primary source
MGI:MGI:2442177
See related
Ensembl:ENSMUSG00000037773 AllianceGenome:MGI:2442177
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Fam113a; A930025D01Rik
Summary
Orthologous to human PCED1A (PC-esterase domain containing 1A). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in ovary adult (RPKM 12.2), limb E14.5 (RPKM 11.2) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Pced1a in Genome Data Viewer
Location:
2; 2 F1
Exon count:
10
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (130259603..130266678, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (130417683..130424641, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1700020A23 gene Neighboring gene transmembrane 239 Neighboring gene VSP16 CORVET/HOPS core subunit Neighboring gene predicted gene, 52562 Neighboring gene protein tyrosine phosphatase, receptor type, A Neighboring gene VISTA enhancer mm1313

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. High-throughput discovery of novel developmental phenotypes. Dickinson ME, et al. Nature, 2016 Sep 22. PMID 27626380, Free PMC Article
  2. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article
  3. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  4. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

See all (16) citations in PubMed

See citations in PubMed for homologs of this gene provided by HomoloGene

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
PC-esterase domain-containing protein 1A
Names
family with sequence similarity 113, member A
protein FAM113A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001114541.2 → NP_001108013.1  PC-esterase domain-containing protein 1A

    See identical proteins and their annotated locations for NP_001108013.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks a segment in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    BX890605
    Consensus CDS
    CCDS50711.1
    UniProtKB/Swiss-Prot
    A2BI89, Q6P1Z5
    UniProtKB/TrEMBL
    Q8BFT7, Q8BUZ8
    Related
    ENSMUSP00000105906.2, ENSMUST00000110277.2
    Conserved Domains (1) summary
    cd01842
    Location:34 → 266
    SGNH_hydrolase_like_5; SGNH_hydrolase subfamily. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site ...

  2. NM_178762.5 → NP_848877.2  PC-esterase domain-containing protein 1A

    See identical proteins and their annotated locations for NP_848877.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer transcript. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    BX890605
    Consensus CDS
    CCDS50711.1
    UniProtKB/Swiss-Prot
    A2BI89, Q6P1Z5
    UniProtKB/TrEMBL
    Q8BFT7, Q8BUE8
    Related
    ENSMUSP00000087009.5, ENSMUST00000089581.11
    Conserved Domains (1) summary
    cd01842
    Location:34 → 266
    SGNH_hydrolase_like_5; SGNH_hydrolase subfamily. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    130259603..130266678 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036162287.1 → XP_036018180.1  PC-esterase domain-containing protein 1A isoform X2

    Conserved Domains (1) summary
    cl01053
    Location:34 → 266
    SGNH_hydrolase; or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the typical ...

  2. XM_036162290.1 → XP_036018183.1  PC-esterase domain-containing protein 1A isoform X5

    Conserved Domains (1) summary
    cl01053
    Location:34 → 266
    SGNH_hydrolase; or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the typical ...

  3. XM_036162288.1 → XP_036018181.1  PC-esterase domain-containing protein 1A isoform X3

    Conserved Domains (1) summary
    cl01053
    Location:34 → 266
    SGNH_hydrolase; or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the typical ...

  4. XM_036162289.1 → XP_036018182.1  PC-esterase domain-containing protein 1A isoform X4

    UniProtKB/TrEMBL
    Q8BFT7
    Conserved Domains (1) summary
    cl01053
    Location:1 → 113
    SGNH_hydrolase; or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the typical ...

  5. XM_017318973.2 → XP_017174462.1  PC-esterase domain-containing protein 1A isoform X1

    UniProtKB/Swiss-Prot
    A2BI89, Q6P1Z5
    Conserved Domains (1) summary
    cd01842
    Location:34 → 266
    SGNH_hydrolase_like_5; SGNH_hydrolase subfamily. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site ...
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6P1Z5.2 GenPept UniProtKB/Swiss-Prot:Q6P1Z5

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