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Itga11 integrin alpha 11 [ Mus musculus (house mouse) ]

Gene ID: 319480, updated on 12-Aug-2019

Summary

Official Symbol
Itga11provided by MGI
Official Full Name
integrin alpha 11provided by MGI
Primary source
MGI:MGI:2442114
See related
Ensembl:ENSMUSG00000032243
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4732459H24Rik
Expression
Broad expression in limb E14.5 (RPKM 7.7), bladder adult (RPKM 6.3) and 18 other tissues See more
Orthologs

Genomic context

See Itga11 in Genome Data Viewer
Location:
9; 9 B
Exon count:
30
Annotation release Status Assembly Chr Location
108 current GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (62677855..62783979)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (62525662..62631786)

Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 39352 Neighboring gene predicted gene, 39353 Neighboring gene dCTP pyrophosphatase 1 pseudogene Neighboring gene fem 1 homolog b

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (4)  1 citation
  • Chemically induced (ENU) (1) 
  • Endonuclease-mediated (1) 

Pathways from PubChem

General gene information

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
collagen binding ISO
Inferred from Sequence Orthology
more info
 
collagen binding involved in cell-matrix adhesion ISO
Inferred from Sequence Orthology
more info
 
collagen receptor activity ISO
Inferred from Sequence Orthology
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
cell adhesion IEA
Inferred from Electronic Annotation
more info
 
cell adhesion mediated by integrin ISO
Inferred from Sequence Orthology
more info
 
cell-matrix adhesion ISO
Inferred from Sequence Orthology
more info
 
collagen-activated signaling pathway ISO
Inferred from Sequence Orthology
more info
 
integrin-mediated signaling pathway ISO
Inferred from Sequence Orthology
more info
 
substrate-dependent cell migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
substrate-dependent cell migration ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
focal adhesion ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
integrin alpha11-beta1 complex ISO
Inferred from Sequence Orthology
more info
 
integrin complex IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
integrin alpha-11
Names
integrin a11

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_176922.5NP_795896.4  integrin alpha-11 precursor

    See identical proteins and their annotated locations for NP_795896.4

    Status: VALIDATED

    Source sequence(s)
    AK028821, AY124460, BB731359, BB840351
    Consensus CDS
    CCDS23265.1
    UniProtKB/TrEMBL
    A0A0B4J1F0, Q7TQC3, Q8CE84
    Related
    ENSMUSP00000034774.8, ENSMUST00000034774.8
    Conserved Domains (3) summary
    smart00191
    Location:538592
    Int_alpha; Integrin alpha (beta-propellor repeats)
    cd01469
    Location:163341
    vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
    pfam08441
    Location:6351034
    Integrin_alpha2; Integrin alpha

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p6 C57BL/6J

Genomic

  1. NC_000075.6 Reference GRCm38.p6 C57BL/6J

    Range
    62677855..62783979
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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