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H2bc18 H2B clustered histone 18 [ Mus musculus (house mouse) ]

Gene ID: 319189, updated on 8-Dec-2022

Summary

Official Symbol
H2bc18provided by MGI
Official Full Name
H2B clustered histone 18provided by MGI
Primary source
MGI:MGI:2448413
See related
Ensembl:ENSMUSG00000105827 AllianceGenome:MGI:2448413
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
H2b-616; Hist2h2bb
Summary
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-dependent histone that is a member of the histone H2B family. [provided by RefSeq, Aug 2015]
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Genomic context

See H2bc18 in Genome Data Viewer
Location:
3; 3 F2.1
Exon count:
1
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (96177016..96177508)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (96269700..96270192)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene H4 clustered histone 14 Neighboring gene H3 clustered histone 13 Neighboring gene Fc receptor, IgG, high affinity I Neighboring gene nuclear encoded tRNA asparagine 4 (anticodon GTT)

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Component Evidence Code Pubs
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
histone H2B type 2-B
Names
H2b 616
histone 2, H2bb
histone cluster 2, H2bb

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_175666.3NP_783597.2  histone H2B type 2-B

    See identical proteins and their annotated locations for NP_783597.2

    Status: VALIDATED

    Source sequence(s)
    AC125099
    Consensus CDS
    CCDS57243.1
    UniProtKB/Swiss-Prot
    Q64525
    UniProtKB/TrEMBL
    A0A6P5PGT2, A0A8C6IFY8
    Related
    ENSMUSP00000135427.2, ENSMUST00000177113.2
    Conserved Domains (1) summary
    smart00427
    Location:28124
    H2B; Histone H2B

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    96177016..96177508
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)