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H2bc3 H2B clustered histone 3 [ Mus musculus (house mouse) ]

Gene ID: 319178, updated on 5-Jan-2023

Summary

Official Symbol
H2bc3provided by MGI
Official Full Name
H2B clustered histone 3provided by MGI
Primary source
MGI:MGI:2448377
See related
Ensembl:ENSMUSG00000075031 AllianceGenome:MGI:2448377
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
H2b-143; Hist1h2bb
Summary
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. [provided by RefSeq, Aug 2015]
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Genomic context

See H2bc3 in Genome Data Viewer
Location:
13; 13 A3.1
Exon count:
1
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (23930717..23931206)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (23746734..23747223)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene H3 clustered histone 3 Neighboring gene H2A clustered histone 5, pseudogene Neighboring gene H2A clustered histone 4 Neighboring gene H3 clustered histone 2

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
 
enables structural constituent of chromatin IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm TAS
Traceable Author Statement
more info
 
part_of nucleosome IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
histone H2B type 1-B
Names
histone 1, H2bb
histone cluster 1, H2bb

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_175664.3NP_783595.1  histone H2B type 1-B

    See identical proteins and their annotated locations for NP_783595.1

    Status: REVIEWED

    Source sequence(s)
    AL590388
    Consensus CDS
    CCDS26363.1
    UniProtKB/Swiss-Prot
    Q14AF8, Q64475
    UniProtKB/TrEMBL
    A0A6P5QWQ2
    Related
    ENSMUSP00000097294.3, ENSMUST00000099703.5
    Conserved Domains (1) summary
    smart00427
    Location:28124
    H2B; Histone H2B

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    23930717..23931206
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)