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H2ac20 H2A clustered histone 20 [ Mus musculus (house mouse) ]

Gene ID: 319176, updated on 26-Sep-2022

Summary

Official Symbol
H2ac20provided by MGI
Official Full Name
H2A clustered histone 20provided by MGI
Primary source
MGI:MGI:2448316
See related
Ensembl:ENSMUSG00000068855 AllianceGenome:MGI:2448316
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
H2a-613b; Hist2h2ac
Summary
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. [provided by RefSeq, Aug 2015]
Orthologs
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Genomic context

See H2ac20 in Genome Data Viewer
Location:
3; 3 F2.1
Exon count:
1
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (96127729..96128196, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (96220413..96220880, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene bolA-like 1 (E. coli) Neighboring gene H2A clustered histone 21 Neighboring gene H2B clustered histone 21 Neighboring gene H3 clustered histone 15

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
 
enables structural constituent of chromatin IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
 
part_of nucleosome IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
histone H2A type 2-C
Names
histone 2, H2ac
histone cluster 2, H2ac

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_175662.3NP_783593.1  histone H2A type 2-C

    See identical proteins and their annotated locations for NP_783593.1

    Status: VALIDATED

    Source sequence(s)
    AC125099
    Consensus CDS
    CCDS17634.1
    UniProtKB/Swiss-Prot
    Q64523, Q8CGP3
    UniProtKB/TrEMBL
    A0A6P5PHI6, Q149V4
    Related
    ENSMUSP00000088288.4, ENSMUST00000090782.4
    Conserved Domains (1) summary
    PTZ00017
    Location:1129
    PTZ00017; histone H2A; Provisional

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    96127729..96128196 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)