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H2ac1 H2A clustered histone 1 [ Mus musculus (house mouse) ]

Gene ID: 319163, updated on 26-Sep-2022


Official Symbol
H2ac1provided by MGI
Official Full Name
H2A clustered histone 1provided by MGI
Primary source
See related
Ensembl:ENSMUSG00000060081 AllianceGenome:MGI:2448285
Gene type
protein coding
RefSeq status
Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Th2a; Hist1h2aa
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene contain a palindromic termination element. [provided by RefSeq, Aug 2015]
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Genomic context

See H2ac1 in Genome Data Viewer
13; 13 A3.1
Exon count:
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (24118420..24118896)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (23934437..23934913)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene U1 small nuclear ribonucleoprotein 1C, pseudogene 2 Neighboring gene predicted gene, 33516 Neighboring gene H2B clustered histone 1 Neighboring gene secretagogin, EF-hand calcium binding protein Neighboring gene capping protein regulator and myosin 1 linker 1 Neighboring gene predicted gene, 33573

Genomic regions, transcripts, and products


General gene information


Clone Names

  • MGC130330, MGC130331

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
Process Evidence Code Pubs
acts_upstream_of_or_within chromatin organization IDA
Inferred from Direct Assay
more info
Component Evidence Code Pubs
located_in female germ cell nucleus IDA
Inferred from Direct Assay
more info

General protein information

Preferred Names
histone cluster 1, H2aa
histone 1, H2aa

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_175658.3NP_783589.1  histone cluster 1, H2aa

    See identical proteins and their annotated locations for NP_783589.1

    Status: REVIEWED

    Source sequence(s)
    Consensus CDS
    A0A8C6IAE0, Q8CGP4
    ENSMUSP00000072227.2, ENSMUST00000072391.2
    Conserved Domains (2) summary
    PTZ00017; histone H2A; Provisional
    H2A; Histone 2A; H2A is a subunit of the nucleosome. The nucleosome is an octamer containing two H2A, H2B, H3, and H4 subunits. The H2A subunit performs essential roles in maintaining structural integrity of the nucleosome, chromatin condensation, and binding ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J


  1. NC_000079.7 Reference GRCm39 C57BL/6J

    GenBank, FASTA, Sequence Viewer (Graphics)