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p24-2 p24-related-2 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 318890, updated on 4-Jan-2025

Summary

Official Symbol
p24-2provided by FlyBase
Official Full Name
p24-related-2provided by FlyBase
Primary source
FLYBASE:FBgn0053105
Locus tag
Dmel_CG33105
See related
AllianceGenome:FB:FBgn0053105
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG33105; CG9443; Dmel\CG33105; p24
Summary
Predicted to enable cargo receptor activity. Predicted to be involved in Golgi organization; endoplasmic reticulum to Golgi vesicle-mediated transport; and intracellular protein transport. Predicted to be located in membrane. Predicted to be active in several cellular components, including COPII-coated ER to Golgi transport vesicle; Golgi apparatus; and endoplasmic reticulum-Golgi intermediate compartment. Is expressed in several structures, including adult brain; adult fat body; adult ventral nerve cord; egg chamber; and gland. Orthologous to several human genes including TMED4 (transmembrane p24 trafficking protein 4). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

See p24-2 in Genome Data Viewer
Location:
85E4-85E4; 3-49 cM
Exon count:
10
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (9687402..9692794, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (5513124..5518516, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene eclair Neighboring gene Uncoordinated 115b Neighboring gene uncharacterized protein Neighboring gene Uncoordinated 115a Neighboring gene trabid

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables cargo receptor activity ISM
Inferred from Sequence Model
more info
PubMed 
Process Evidence Code Pubs
involved_in Golgi organization IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in Golgi vesicle transport ISM
Inferred from Sequence Model
more info
PubMed 
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in COPII-coated ER to Golgi transport vesicle IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in endoplasmic reticulum-Golgi intermediate compartment IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane ISM
Inferred from Sequence Model
more info
PubMed 

General protein information

Preferred Names
p24-related-2
Names
CG33105-PA
CG33105-PB
p24-2-PA
p24-2-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    9687402..9692794 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001202276.2NP_001189205.1  p24-related-2, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001189205.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q86BA5
    Conserved Domains (1) summary
    pfam01105
    Location:20206
    EMP24_GP25L; emp24/gp25L/p24 family/GOLD
  2. NM_176440.1NP_788617.1  p24-related-2, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_788617.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q86BA5
    Related
    FBpp0081571, FBtr0082093
    Conserved Domains (1) summary
    pfam01105
    Location:20206
    EMP24_GP25L; emp24/gp25L/p24 family/GOLD