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HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 [ Homo sapiens (human) ]

Gene ID: 3187, updated on 4-May-2020

Summary

Official Symbol
HNRNPH1provided by HGNC
Official Full Name
heterogeneous nuclear ribonucleoprotein H1provided by HGNC
Primary source
HGNC:HGNC:5041
See related
Ensembl:ENSG00000169045 MIM:601035
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HNRPH; HNRPH1; hnRNPH
Summary
This gene encodes a member of a subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA. These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some may shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNA and is very similar to the family member HNRPF. This gene may be associated with hereditary lymphedema type I. Alternatively spliced transcript variants have been described [provided by RefSeq, Mar 2012]
Expression
Ubiquitous expression in bone marrow (RPKM 153.8), lymph node (RPKM 101.7) and 25 other tissues See more
Orthologs

Genomic context

See HNRNPH1 in Genome Data Viewer
Location:
5q35.3
Exon count:
19
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 5 NC_000005.10 (179614178..179634784, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (179041179..179050722, complement)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene RUN and FYVE domain containing 1 Neighboring gene peroxiredoxin 2 pseudogene 3 Neighboring gene RUFY1 antisense RNA 1 Neighboring gene Sharpr-MPRA regulatory region 11836 Neighboring gene chromosome 5 open reading frame 60 Neighboring gene chromosome 5 open reading frame 60 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

HIV-1 interactions

Replication interactions

Interaction Pubs
Knockdown of heterogeneous nuclear ribonucleoprotein H1 (HNRNPH1) by siRNA inhibits the early stages of HIV-1 replication in 293T cells infected with VSV-G pseudotyped HIV-1 PubMed

Protein interactions

Protein Gene Interaction Pubs
Envelope surface glycoprotein gp120 env Tandem affinity purification and mass spectrometry analysis identify heterogeneous nuclear ribonucleoprotein H1 (HNRNPH1), HIV-1 Gag, Gag/Pol, gp120, and Nef incorporated into staufen1 RNP complexes isolated from HIV-1-expressing cells PubMed
Gag-Pol gag-pol Tandem affinity purification and mass spectrometry analysis identify heterogeneous nuclear ribonucleoprotein H1 (HNRNPH1), HIV-1 Gag, Gag/Pol, gp120, and Nef incorporated into staufen1 RNP complexes isolated from HIV-1-expressing cells PubMed
Nef nef Tandem affinity purification and mass spectrometry analysis identify heterogeneous nuclear ribonucleoprotein H1 (HNRNPH1), HIV-1 Gag, Gag/Pol, gp120, and Nef incorporated into staufen1 RNP complexes isolated from HIV-1-expressing cells PubMed
Pr55(Gag) gag Tandem affinity purification and mass spectrometry analysis identify heterogeneous nuclear ribonucleoprotein H1 (HNRNPH1), HIV-1 Gag, Gag/Pol, gp120, and Nef incorporated into staufen1 RNP complexes isolated from HIV-1-expressing cells PubMed
Rev rev HIV-1 Rev interacting protein, heterogeneous nuclear ribonucleoprotein H1 (HNRNPH1), is identified by the in-vitro binding experiments involving cytosolic or nuclear extracts from HeLa cells. The interaction of Rev with HNRNPH1 is increased by RRE PubMed
Vif vif Proteins hnRNP F, hnRNP H, and hnRNP A2/B1 bind to the intronic G run (G13-2: AGGGA) to regulate the levels of vif and vpr mRNA, and the amounts of Vif and Vpr protein expression PubMed
vif Proteins hnRNP F, hnRNP H, and hnRNP A2/B1 bind to the intronic G run (G12-1: AGGGA) to regulate the levels of vif mRNA and Vif protein expression PubMed
Vpr vpr Proteins hnRNP F, hnRNP H, and hnRNP A2/B1 bind to the intronic G run (G13-2: AGGGA) to regulate the levels of vif and vpr mRNA, and the amounts of Vif and Vpr protein expression PubMed

Go to the HIV-1, Human Interaction Database

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • DKFZp686A15170

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA binding HDA PubMed 
RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
RNA binding IDA
Inferred from Direct Assay
more info
PubMed 
poly(U) RNA binding TAS
Traceable Author Statement
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
RNA metabolic process TAS
Traceable Author Statement
more info
 
RNA processing TAS
Traceable Author Statement
more info
PubMed 
fibroblast growth factor receptor signaling pathway TAS
Traceable Author Statement
more info
 
mRNA splicing, via spliceosome IC
Inferred by Curator
more info
PubMed 
mRNA splicing, via spliceosome TAS
Traceable Author Statement
more info
 
regulation of RNA splicing IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of RNA splicing IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
catalytic step 2 spliceosome IDA
Inferred from Direct Assay
more info
PubMed 
cytosol IDA
Inferred from Direct Assay
more info
 
membrane HDA PubMed 
nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleoplasm IDA
Inferred from Direct Assay
more info
 
nucleoplasm TAS
Traceable Author Statement
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
ribonucleoprotein complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
heterogeneous nuclear ribonucleoprotein H
Names
epididymis secretory sperm binding protein
heterogeneous nuclear ribonucleoprotein H1 (H)

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001257293.2NP_001244222.1  heterogeneous nuclear ribonucleoprotein H isoform a

    See identical proteins and their annotated locations for NP_001244222.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Variants 1 and 2 both encode the same isoform (a).
    Source sequence(s)
    BC001348, BQ028714, DA204744
    Consensus CDS
    CCDS4446.1
    UniProtKB/Swiss-Prot
    P31943
    Related
    ENSP00000377082.4, ENST00000393432.8
    Conserved Domains (4) summary
    cd12729
    Location:1088
    RRM1_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    cd12734
    Location:289364
    RRM3_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    pfam08080
    Location:255290
    zf-RNPHF; RNPHF zinc finger
    cl17169
    Location:93188
    RRM_SF; RNA recognition motif (RRM) superfamily
  2. NM_001363572.2NP_001350501.1  heterogeneous nuclear ribonucleoprotein H isoform b

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR, uses an alternate in-frame splice junction, and lacks an alternate in-frame exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a.
    Source sequence(s)
    AC136604
    Consensus CDS
    CCDS87357.1
    Related
    ENSP00000426275.1, ENST00000510411.5
    Conserved Domains (4) summary
    cd12729
    Location:1088
    RRM1_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    cd12734
    Location:289364
    RRM3_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    pfam08080
    Location:255290
    zf-RNPHF; RNPHF zinc finger
    cl17169
    Location:93188
    RRM_SF; RNA recognition motif (RRM) superfamily
  3. NM_001364225.1NP_001351154.1  heterogeneous nuclear ribonucleoprotein H isoform c

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4), as well as variants 5-8, encodes the longest isoform (c).
    Source sequence(s)
    AC136604
    Conserved Domains (4) summary
    cd12729
    Location:1088
    RRM1_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    cd12734
    Location:289364
    RRM3_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    pfam08080
    Location:255290
    zf-RNPHF; RNPHF zinc finger
    cl17169
    Location:93188
    RRM_SF; RNA recognition motif (RRM) superfamily
  4. NM_001364226.1NP_001351155.1  heterogeneous nuclear ribonucleoprotein H isoform c

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5), as well as variants 4 and 6-8, encodes isoform c.
    Source sequence(s)
    AC136604
    Conserved Domains (4) summary
    cd12729
    Location:1088
    RRM1_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    cd12734
    Location:289364
    RRM3_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    pfam08080
    Location:255290
    zf-RNPHF; RNPHF zinc finger
    cl17169
    Location:93188
    RRM_SF; RNA recognition motif (RRM) superfamily
  5. NM_001364227.2NP_001351156.1  heterogeneous nuclear ribonucleoprotein H isoform c

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6), as well as variants 4, 5, 7, and 8, encodes isoform c.
    Source sequence(s)
    AC136604
    Conserved Domains (4) summary
    cd12729
    Location:1088
    RRM1_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    cd12734
    Location:289364
    RRM3_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    pfam08080
    Location:255290
    zf-RNPHF; RNPHF zinc finger
    cl17169
    Location:93188
    RRM_SF; RNA recognition motif (RRM) superfamily
  6. NM_001364228.2NP_001351157.1  heterogeneous nuclear ribonucleoprotein H isoform c

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7), as well as variants 4-6 and 8, encodes isoform c.
    Source sequence(s)
    AC136604
    Related
    ENSP00000327539.6, ENST00000329433.10
    Conserved Domains (4) summary
    cd12729
    Location:1088
    RRM1_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    cd12734
    Location:289364
    RRM3_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    pfam08080
    Location:255290
    zf-RNPHF; RNPHF zinc finger
    cl17169
    Location:93188
    RRM_SF; RNA recognition motif (RRM) superfamily
  7. NM_001364229.2NP_001351158.1  heterogeneous nuclear ribonucleoprotein H isoform c

    Status: REVIEWED

    Description
    Transcript Variant: This variant (8), as well as variants 4-7, encodes isoform c.
    Source sequence(s)
    AC136604
    Conserved Domains (4) summary
    cd12729
    Location:1088
    RRM1_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    cd12734
    Location:289364
    RRM3_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    pfam08080
    Location:255290
    zf-RNPHF; RNPHF zinc finger
    cl17169
    Location:93188
    RRM_SF; RNA recognition motif (RRM) superfamily
  8. NM_001364230.2NP_001351159.1  heterogeneous nuclear ribonucleoprotein H isoform d

    Status: REVIEWED

    Description
    Transcript Variant: This variant (9), as well as variants 10 and 11, encodes isoform d.
    Source sequence(s)
    AC136604
    Conserved Domains (4) summary
    cd12729
    Location:1088
    RRM1_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    cd12734
    Location:289364
    RRM3_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    pfam08080
    Location:255290
    zf-RNPHF; RNPHF zinc finger
    cl17169
    Location:93188
    RRM_SF; RNA recognition motif (RRM) superfamily
  9. NM_001364231.2NP_001351160.1  heterogeneous nuclear ribonucleoprotein H isoform d

    Status: REVIEWED

    Description
    Transcript Variant: This variant (10), as well as variants 9 and 11, encodes isoform d.
    Source sequence(s)
    AC136604
    Conserved Domains (4) summary
    cd12729
    Location:1088
    RRM1_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    cd12734
    Location:289364
    RRM3_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    pfam08080
    Location:255290
    zf-RNPHF; RNPHF zinc finger
    cl17169
    Location:93188
    RRM_SF; RNA recognition motif (RRM) superfamily
  10. NM_001364232.2NP_001351161.1  heterogeneous nuclear ribonucleoprotein H isoform d

    Status: REVIEWED

    Description
    Transcript Variant: This variant (11), as well as variants 9 and 10, encodes isoform d.
    Source sequence(s)
    AC136604
    Conserved Domains (4) summary
    cd12729
    Location:1088
    RRM1_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    cd12734
    Location:289364
    RRM3_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    pfam08080
    Location:255290
    zf-RNPHF; RNPHF zinc finger
    cl17169
    Location:93188
    RRM_SF; RNA recognition motif (RRM) superfamily
  11. NM_001364233.1NP_001351162.1  heterogeneous nuclear ribonucleoprotein H isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (12), as well as variants 1, 2, and 13-18, encodes isoform a.
    Source sequence(s)
    AC136604
    Conserved Domains (4) summary
    cd12729
    Location:1088
    RRM1_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    cd12734
    Location:289364
    RRM3_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    pfam08080
    Location:255290
    zf-RNPHF; RNPHF zinc finger
    cl17169
    Location:93188
    RRM_SF; RNA recognition motif (RRM) superfamily
  12. NM_001364234.1NP_001351163.1  heterogeneous nuclear ribonucleoprotein H isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (13), as well as variants 1, 2, 12, and 14-18, encodes isoform a.
    Source sequence(s)
    AC136604
    Conserved Domains (4) summary
    cd12729
    Location:1088
    RRM1_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    cd12734
    Location:289364
    RRM3_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    pfam08080
    Location:255290
    zf-RNPHF; RNPHF zinc finger
    cl17169
    Location:93188
    RRM_SF; RNA recognition motif (RRM) superfamily
  13. NM_001364235.1NP_001351164.1  heterogeneous nuclear ribonucleoprotein H isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (14), as well as variants 1, 2, 12, 13, and 15-18, encodes isoform a.
    Source sequence(s)
    AC136604
    Conserved Domains (4) summary
    cd12729
    Location:1088
    RRM1_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    cd12734
    Location:289364
    RRM3_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    pfam08080
    Location:255290
    zf-RNPHF; RNPHF zinc finger
    cl17169
    Location:93188
    RRM_SF; RNA recognition motif (RRM) superfamily
  14. NM_001364236.2NP_001351165.1  heterogeneous nuclear ribonucleoprotein H isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (15), as well as variants 1, 2, 12-14, and 16-18, encodes isoform a.
    Source sequence(s)
    AC136604
    Related
    ENSP00000349168.5, ENST00000356731.9
    Conserved Domains (4) summary
    cd12729
    Location:1088
    RRM1_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    cd12734
    Location:289364
    RRM3_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    pfam08080
    Location:255290
    zf-RNPHF; RNPHF zinc finger
    cl17169
    Location:93188
    RRM_SF; RNA recognition motif (RRM) superfamily
  15. NM_001364237.2NP_001351166.1  heterogeneous nuclear ribonucleoprotein H isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (16), as well as variants 1, 2, 12-15, 17 and 18, encodes isoform a.
    Source sequence(s)
    AC136604
    Conserved Domains (4) summary
    cd12729
    Location:1088
    RRM1_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    cd12734
    Location:289364
    RRM3_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    pfam08080
    Location:255290
    zf-RNPHF; RNPHF zinc finger
    cl17169
    Location:93188
    RRM_SF; RNA recognition motif (RRM) superfamily
  16. NM_001364238.2NP_001351167.1  heterogeneous nuclear ribonucleoprotein H isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (17), as well as variants 1, 2, 12-16, and 18, encodes isoform a.
    Source sequence(s)
    AC136604
    Conserved Domains (4) summary
    cd12729
    Location:1088
    RRM1_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    cd12734
    Location:289364
    RRM3_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    pfam08080
    Location:255290
    zf-RNPHF; RNPHF zinc finger
    cl17169
    Location:93188
    RRM_SF; RNA recognition motif (RRM) superfamily
  17. NM_001364239.2NP_001351168.1  heterogeneous nuclear ribonucleoprotein H isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (18), as well as variants 1, 2, and 12-17, encodes isoform a.
    Source sequence(s)
    AC136604
    Conserved Domains (4) summary
    cd12729
    Location:1088
    RRM1_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    cd12734
    Location:289364
    RRM3_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    pfam08080
    Location:255290
    zf-RNPHF; RNPHF zinc finger
    cl17169
    Location:93188
    RRM_SF; RNA recognition motif (RRM) superfamily
  18. NM_001364240.2NP_001351169.1  heterogeneous nuclear ribonucleoprotein H isoform e

    Status: REVIEWED

    Source sequence(s)
    AC136604
    Conserved Domains (4) summary
    cd12729
    Location:1088
    RRM1_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    cd12734
    Location:282357
    RRM3_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    pfam08080
    Location:255283
    zf-RNPHF; RNPHF zinc finger
    cl17169
    Location:93188
    RRM_SF; RNA recognition motif (RRM) superfamily
  19. NM_001364241.2NP_001351170.1  heterogeneous nuclear ribonucleoprotein H isoform f

    Status: REVIEWED

    Description
    Transcript Variant: This variant (20), as well as variants 21and 22, encodes isoform f.
    Source sequence(s)
    AC136604
    Conserved Domains (4) summary
    cd12729
    Location:1088
    RRM1_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    cd12734
    Location:282357
    RRM3_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    pfam08080
    Location:255283
    zf-RNPHF; RNPHF zinc finger
    cl17169
    Location:93188
    RRM_SF; RNA recognition motif (RRM) superfamily
  20. NM_001364242.2NP_001351171.1  heterogeneous nuclear ribonucleoprotein H isoform f

    Status: REVIEWED

    Description
    Transcript Variant: This variant (21), as well as variants 20 and 22, encodes isoform f.
    Source sequence(s)
    AC136604
    Conserved Domains (4) summary
    cd12729
    Location:1088
    RRM1_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    cd12734
    Location:282357
    RRM3_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    pfam08080
    Location:255283
    zf-RNPHF; RNPHF zinc finger
    cl17169
    Location:93188
    RRM_SF; RNA recognition motif (RRM) superfamily
  21. NM_001364243.2NP_001351172.1  heterogeneous nuclear ribonucleoprotein H isoform f

    Status: REVIEWED

    Description
    Transcript Variant: This variant (22), as well as variants 20 and 21, encodes isoform f.
    Source sequence(s)
    AC136604
    Conserved Domains (4) summary
    cd12729
    Location:1088
    RRM1_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    cd12734
    Location:282357
    RRM3_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    pfam08080
    Location:255283
    zf-RNPHF; RNPHF zinc finger
    cl17169
    Location:93188
    RRM_SF; RNA recognition motif (RRM) superfamily
  22. NM_001364244.2NP_001351173.1  heterogeneous nuclear ribonucleoprotein H isoform g

    Status: REVIEWED

    Source sequence(s)
    AC136604
    Conserved Domains (4) summary
    cd12729
    Location:1088
    RRM1_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    cd12734
    Location:289364
    RRM3_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    pfam08080
    Location:255290
    zf-RNPHF; RNPHF zinc finger
    cl17169
    Location:93188
    RRM_SF; RNA recognition motif (RRM) superfamily
  23. NM_001364245.2NP_001351174.1  heterogeneous nuclear ribonucleoprotein H isoform b

    Status: REVIEWED

    Description
    Transcript Variant: This variant (24), as well as variants 3, 25, and 26, encodes isoform b.
    Source sequence(s)
    AC136604
    Conserved Domains (4) summary
    cd12729
    Location:1088
    RRM1_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    cd12734
    Location:289364
    RRM3_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    pfam08080
    Location:255290
    zf-RNPHF; RNPHF zinc finger
    cl17169
    Location:93188
    RRM_SF; RNA recognition motif (RRM) superfamily
  24. NM_001364246.2NP_001351175.1  heterogeneous nuclear ribonucleoprotein H isoform b

    Status: REVIEWED

    Description
    Transcript Variant: This variant (25), as well as variants 3, 24, and 26, encodes isoform b.
    Source sequence(s)
    AC136604
    Conserved Domains (4) summary
    cd12729
    Location:1088
    RRM1_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    cd12734
    Location:289364
    RRM3_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    pfam08080
    Location:255290
    zf-RNPHF; RNPHF zinc finger
    cl17169
    Location:93188
    RRM_SF; RNA recognition motif (RRM) superfamily
  25. NM_001364247.2NP_001351176.1  heterogeneous nuclear ribonucleoprotein H isoform b

    Status: REVIEWED

    Description
    Transcript Variant: This variant (26), as well as variants 3, 24, and 25, encodes isoform b.
    Source sequence(s)
    AC136604
    Conserved Domains (4) summary
    cd12729
    Location:1088
    RRM1_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    cd12734
    Location:289364
    RRM3_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    pfam08080
    Location:255290
    zf-RNPHF; RNPHF zinc finger
    cl17169
    Location:93188
    RRM_SF; RNA recognition motif (RRM) superfamily
  26. NM_001364248.2NP_001351177.1  heterogeneous nuclear ribonucleoprotein H isoform h

    Status: REVIEWED

    Source sequence(s)
    AC136604
    Conserved Domains (4) summary
    cd12729
    Location:1088
    RRM1_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    cd12734
    Location:282357
    RRM3_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    pfam08080
    Location:255283
    zf-RNPHF; RNPHF zinc finger
    cl17169
    Location:93188
    RRM_SF; RNA recognition motif (RRM) superfamily
  27. NM_001364250.2NP_001351179.1  heterogeneous nuclear ribonucleoprotein H isoform i

    Status: REVIEWED

    Source sequence(s)
    AC136604
    Conserved Domains (3) summary
    cd12734
    Location:237312
    RRM3_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    pfam08080
    Location:203238
    zf-RNPHF; RNPHF zinc finger
    cl17169
    Location:41136
    RRM_SF; RNA recognition motif (RRM) superfamily
  28. NM_001364251.2NP_001351180.1  heterogeneous nuclear ribonucleoprotein H isoform j

    Status: REVIEWED

    Description
    Transcript Variant: This variant (29), as well as variants 30 and 31, encodes isoform j.
    Source sequence(s)
    AC136604
    Conserved Domains (2) summary
    cd12734
    Location:88163
    RRM3_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    pfam08080
    Location:5489
    zf-RNPHF; RNPHF zinc finger
  29. NM_001364252.2NP_001351181.1  heterogeneous nuclear ribonucleoprotein H isoform j

    Status: REVIEWED

    Description
    Transcript Variant: This variant (30), as well as variants 29 and 31, encodes isoform j.
    Source sequence(s)
    AC136604
    Conserved Domains (2) summary
    cd12734
    Location:88163
    RRM3_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    pfam08080
    Location:5489
    zf-RNPHF; RNPHF zinc finger
  30. NM_001364253.1NP_001351182.1  heterogeneous nuclear ribonucleoprotein H isoform j

    Status: REVIEWED

    Description
    Transcript Variant: This variant (31), as well as variants 29 and 30, encodes isoform j.
    Source sequence(s)
    AC136604
    Conserved Domains (2) summary
    cd12734
    Location:88163
    RRM3_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    pfam08080
    Location:5489
    zf-RNPHF; RNPHF zinc finger
  31. NM_001364254.2NP_001351183.1  heterogeneous nuclear ribonucleoprotein H isoform k

    Status: REVIEWED

    Description
    Transcript Variant: This variant (32), as well as variant 33, encodes isoform k.
    Source sequence(s)
    AC136604
    Conserved Domains (2) summary
    cd12734
    Location:88163
    RRM3_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    pfam08080
    Location:5489
    zf-RNPHF; RNPHF zinc finger
  32. NM_001364255.2NP_001351184.1  heterogeneous nuclear ribonucleoprotein H isoform k

    Status: REVIEWED

    Description
    Transcript Variant: This variant (33), as well as variant 32, encodes isoform k.
    Source sequence(s)
    AC136604
    Conserved Domains (2) summary
    cd12734
    Location:88163
    RRM3_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    pfam08080
    Location:5489
    zf-RNPHF; RNPHF zinc finger
  33. NM_005520.3NP_005511.1  heterogeneous nuclear ribonucleoprotein H isoform a

    See identical proteins and their annotated locations for NP_005511.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same isoform (a).
    Source sequence(s)
    AK124530, BC001348, DA603645
    Consensus CDS
    CCDS4446.1
    UniProtKB/Swiss-Prot
    P31943
    Related
    ENSP00000397797.2, ENST00000442819.6
    Conserved Domains (4) summary
    cd12729
    Location:1088
    RRM1_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 1 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    cd12734
    Location:289364
    RRM3_hnRNPH_hnRNPH2_hnRNPF; RNA recognition motif 3 in heterogeneous nuclear ribonucleoprotein hnRNP H , hnRNP H2, hnRNP F and similar proteins
    pfam08080
    Location:255290
    zf-RNPHF; RNPHF zinc finger
    cl17169
    Location:93188
    RRM_SF; RNA recognition motif (RRM) superfamily

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p13 Primary Assembly

    Range
    179614178..179634784 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p13 PATCHES

Genomic

  1. NW_016107298.1 Reference GRCh38.p13 PATCHES

    Range
    380457..401011 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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