Or65a Odorant receptor 65a [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Or65aprovided by FlyBase
Official Full Name: Odorant receptor 65aprovided by FlyBase
Primary source: FLYBASE:FBgn0041625
Locus tag: Dmel_CG32401
See related: AllianceGenome:FB:FBgn0041625
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: 65a; CG32401; Dmel\CG32401; DOR66; LU27.2; or65a; OR65a
Summary: Enables ionotropic olfactory receptor activity. Involved in detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in dendrite membrane. Predicted to be active in plasma membrane. Is expressed in adult antennal lobe; adult olfactory receptor neuron Or65; antennal lobe glomerulus DL3; third segment of antenna; and trichoid sensillum. [provided by Alliance of Genome Resources, Jul 2025]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3L	NT_037436.4 (6320611..6322098)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3L	NT_037436.3 (6313711..6315198)

Chromosome 3L - NT_037436.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Mating suppresses pheromone attraction in Drosophila females via Or65a olfactory neurons.
Title: Love makes smell blind: mating suppresses pheromone attraction in Drosophila females via Or65a olfactory neurons.

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables ionotropic olfactory receptor activity	HDA more info	PubMed
enables odorant binding	IEA Inferred from Electronic Annotation more info
enables odorant binding	ISS Inferred from Sequence or Structural Similarity more info
enables olfactory receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables olfactory receptor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in detection of chemical stimulus involved in sensory perception of smell	HDA more info	PubMed
involved_in detection of chemical stimulus involved in sensory perception of smell	IBA Inferred from Biological aspect of Ancestor more info
involved_in sensory perception of smell	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in dendrite membrane	ISS Inferred from Sequence or Structural Similarity more info
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info