U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Spn75F Serpin 75F [ Drosophila melanogaster (fruit fly) ]

Gene ID: 317912, updated on 5-Jan-2023

Summary

Official Symbol
Spn75Fprovided by FlyBase
Official Full Name
Serpin 75Fprovided by FlyBase
Primary source
FLYBASE:FBgn0052203
Locus tag
Dmel_CG32203
See related
AllianceGenome:FB:FBgn0052203
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
6h1; BG642378; BG642378(6h1); CG32203; Dmel\CG32203
Summary
Involved in multicellular organism reproduction. Located in extracellular space. Is expressed in adult head. Human ortholog(s) of this gene implicated in COVID-19; alpha-2-plasmin inhibitor deficiency; and familial encephalopathy with neuroserpin inclusion bodies. Orthologous to human SERPINF2 (serpin family F member 2) and SERPINI1 (serpin family I member 1). [provided by Alliance of Genome Resources, Apr 2022]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Spn75F in Genome Data Viewer
Location:
75F9-75F9; 3-45 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.46 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (19128450..19129665, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (19121550..19122765, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Gemin 2 Neighboring gene uncharacterized protein Neighboring gene frizzled 2 Neighboring gene long non-coding RNA:CR45941 Neighboring gene long non-coding RNA:CR43893

Genomic regions, transcripts, and products

General protein information

Preferred Names
serpin 75F
Names
BG642378
CG32203-PB
Spn75F-PB

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    19128450..19129665 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001043149.2NP_001036614.1  serpin 75F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001036614.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q3HKQ3
    Related
    FBpp0110068, FBtr0110771
    Conserved Domains (1) summary
    cl00137
    Location:21353
    SERPIN; SERine Proteinase INhibitors (serpins) exhibit conformational polymorphism shifting from native to cleaved, latent, delta, or polymorphic forms. Many serpins, such as antitrypsin and antichymotrypsin, function as serine protease inhibitors which regulate ...