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VN1R4 vomeronasal 1 receptor 4 [ Homo sapiens (human) ]

Gene ID: 317703, updated on 10-Dec-2024

Summary

Official Symbol
VN1R4provided by HGNC
Official Full Name
vomeronasal 1 receptor 4provided by HGNC
Primary source
HGNC:HGNC:19871
See related
Ensembl:ENSG00000228567 AllianceGenome:HGNC:19871
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
V1RL4
Summary
Predicted to enable pheromone receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway; response to pheromone; and sensory perception of chemical stimulus. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See VN1R4 in Genome Data Viewer
Location:
19q13.42
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (53266676..53267723, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (56346170..56347217, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (53769929..53770976, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene zinc finger protein 677 Neighboring gene vomeronasal 1 receptor 2 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr19:53772628-53773290 Neighboring gene family with sequence similarity 90 member A27, pseudogene Neighboring gene baculoviral IAP repeat containing 8

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Markers

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables pheromone receptor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in response to pheromone IEA
Inferred from Electronic Annotation
more info
 
involved_in sensory perception of chemical stimulus IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
vomeronasal type-1 receptor 4
Names
CTD-2245F17.9
G-protein coupled receptor GPCR27
V1R-like 4
V1r-like receptor 4
hGPCR27
pheromone receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_173857.3NP_776256.2  vomeronasal type-1 receptor 4

    See identical proteins and their annotated locations for NP_776256.2

    Status: VALIDATED

    Source sequence(s)
    AC092070
    Consensus CDS
    CCDS33099.1
    UniProtKB/Swiss-Prot
    Q2M3E2, Q7Z5H5, Q7Z5H6, Q7Z5H7, Q8TDU2
    Related
    ENSP00000310856.4, ENST00000311170.5
    Conserved Domains (1) summary
    pfam03402
    Location:36295
    V1R; Vomeronasal organ pheromone receptor family, V1R

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    53266676..53267723 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    56346170..56347217 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)