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VN1R2 vomeronasal 1 receptor 2 [ Homo sapiens (human) ]

Gene ID: 317701, updated on 22-Sep-2022

Summary

Official Symbol
VN1R2provided by HGNC
Official Full Name
vomeronasal 1 receptor 2provided by HGNC
Primary source
HGNC:HGNC:19872
See related
Ensembl:ENSG00000196131 AllianceGenome:HGNC:19872
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
V1RL2
Summary
Predicted to enable pheromone receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and response to pheromone. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See VN1R2 in Genome Data Viewer
Location:
19q13.42
Exon count:
1
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (53258292..53259602)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (56337798..56339108)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (53761545..53762855)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene NADH:ubiquinone oxidoreductase core subunit V2 pseudogene 1 Neighboring gene zinc finger protein 677 Neighboring gene vomeronasal 1 receptor 4 Neighboring gene family with sequence similarity 90 member A27, pseudogene

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables pheromone receptor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in response to pheromone IEA
Inferred from Electronic Annotation
more info
 
involved_in sensory perception of chemical stimulus IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
vomeronasal type-1 receptor 2
Names
G-protein coupled receptor GPCR25
V1R-like 2
V1r-like receptor 2
hGPCR25
pheromone receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_173856.2NP_776255.2  vomeronasal type-1 receptor 2

    See identical proteins and their annotated locations for NP_776255.2

    Status: VALIDATED

    Source sequence(s)
    AC092070, BC130356
    Consensus CDS
    CCDS12862.1
    UniProtKB/Swiss-Prot
    Q8NFZ6, Q8TDU4
    Related
    ENSP00000351244.2, ENST00000341702.3
    Conserved Domains (1) summary
    pfam03402
    Location:118369
    V1R; Vomeronasal organ pheromone receptor family, V1R

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    53258292..53259602
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    56337798..56339108
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)