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FAM149B1 family with sequence similarity 149 member B1 [ Homo sapiens (human) ]

Gene ID: 317662, updated on 24-Nov-2020

Summary

Official Symbol
FAM149B1provided by HGNC
Official Full Name
family with sequence similarity 149 member B1provided by HGNC
Primary source
HGNC:HGNC:29162
See related
Ensembl:ENSG00000138286 MIM:618413
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
JBTS36; KIAA0974
Expression
Ubiquitous expression in testis (RPKM 10.1), brain (RPKM 6.8) and 25 other tissues See more
Orthologs

Genomic context

See FAM149B1 in Genome Data Viewer
Location:
10q22.2
Exon count:
17
Annotation release Status Assembly Chr Location
109.20201120 current GRCh38.p13 (GCF_000001405.39) 10 NC_000010.11 (73168090..73244504)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (74927877..75002435)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene prolyl 4-hydroxylase subunit alpha 1 Neighboring gene nudix hydrolase 13 Neighboring gene small nucleolar RNA, H/ACA box 11F Neighboring gene ecdysoneless cell cycle regulator Neighboring gene uncharacterized LOC105378358 Neighboring gene eukaryotic translation initiation factor 4A2 pseudogene 2 Neighboring gene DNAJC9 antisense RNA 1 Neighboring gene DnaJ heat shock protein family (Hsp40) member C9 Neighboring gene mitochondrial ribosomal protein S16 Neighboring gene cilia and flagella associated protein 70 Neighboring gene RNA, U6 small nuclear 833, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA0974

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
cilium assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein localization to cilium IMP
Inferred from Mutant Phenotype
more info
PubMed 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_173348.2NP_775483.1  protein FAM149B1

    See identical proteins and their annotated locations for NP_775483.1

    Status: VALIDATED

    Source sequence(s)
    AB023191, AC016394, BM977866, DC340839
    Consensus CDS
    CCDS44435.1
    UniProtKB/Swiss-Prot
    Q96BN6
    Related
    ENSP00000242505.6, ENST00000242505.11
    Conserved Domains (1) summary
    pfam12516
    Location:115179
    DUF3719; Protein of unknown function (DUF3719)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20201120

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p13 Primary Assembly

    Range
    73168090..73244504
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017016164.1XP_016871653.1  protein FAM149B1 isoform X4

  2. XM_011539737.2XP_011538039.1  protein FAM149B1 isoform X2

    Conserved Domains (1) summary
    pfam12516
    Location:93157
    DUF3719; Protein of unknown function (DUF3719)
  3. XM_005269745.2XP_005269802.1  protein FAM149B1 isoform X3

    Conserved Domains (1) summary
    pfam12516
    Location:115179
    DUF3719; Protein of unknown function (DUF3719)
  4. XM_005269744.2XP_005269801.1  protein FAM149B1 isoform X1

    Related
    ENSP00000362046.3, ENST00000372955.7
    Conserved Domains (1) summary
    pfam12516
    Location:115179
    DUF3719; Protein of unknown function (DUF3719)
  5. XM_017016167.1XP_016871656.1  protein FAM149B1 isoform X8

  6. XM_011539740.2XP_011538042.1  protein FAM149B1 isoform X9

    Conserved Domains (1) summary
    pfam12516
    Location:115179
    DUF3719; Protein of unknown function (DUF3719)
  7. XM_017016166.1XP_016871655.1  protein FAM149B1 isoform X6

    Related
    ENSP00000402293.1, ENST00000445951.5
    Conserved Domains (1) summary
    pfam05109
    Location:193408
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
  8. XM_005269747.3XP_005269804.1  protein FAM149B1 isoform X6

    Conserved Domains (1) summary
    pfam05109
    Location:193408
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
  9. XM_017016165.1XP_016871654.1  protein FAM149B1 isoform X5

    Conserved Domains (1) summary
    pfam12516
    Location:973
    DUF3719; Protein of unknown function (DUF3719)
  10. XM_024447970.1XP_024303738.1  protein FAM149B1 isoform X7

RNA

  1. XR_945714.2 RNA Sequence

  2. XR_945712.1 RNA Sequence

  3. XR_945713.1 RNA Sequence

  4. XR_001747096.1 RNA Sequence

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