U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

MYH10 myosin heavy chain 10 [ Bos taurus (domestic cattle) ]

Gene ID: 317655, updated on 5-Sep-2025
Official Symbol
MYH10provided by VGNC
Official Full Name
myosin heavy chain 10provided by VGNC
Primary source
VGNC:VGNC:31794
See related
BGD:BT23905; EnsemblRapid:ENSBTAG00070021096
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See MYH10 in Genome Data Viewer
Location:
chromosome: 19
Exon count:
45
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (28061573..28183702, complement)

Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene basic proline-rich protein Neighboring gene ubiquitin-conjugating enzyme E2 B-like Neighboring gene nudE neurodevelopment protein 1 like 1 Neighboring gene ring finger protein 222 Neighboring gene uncharacterized LOC132343043 Neighboring gene small nucleolar RNA SNORA79 Neighboring gene U6 spliceosomal RNA Neighboring gene coiled-coil domain containing 42

Genomic Sequence:
NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Related articles in PubMed

  1. Neuronal cell expression of inserted isoforms of vertebrate nonmuscle myosin heavy chain II-B. Itoh K, et al. J Biol Chem, 1995 Jun 16. PMID 7782316
  2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables actin filament binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables microfilament motor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in actomyosin structure organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mitotic cytokinesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell shape IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of myosin II complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in myosin filament IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
myosin-10
Names
NMMHC II-b
NMMHC-B
NMMHC-IIB
cellular myosin heavy chain, type B
myosin heavy chain, non-muscle IIb
myosin, heavy polypeptide 10, non-muscle
non-muscle myosin heavy chain B
non-muscle myosin heavy chain IIb
nonmuscle myosin heavy chain B

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_174834.1 → NP_777259.1  myosin-10

    See identical proteins and their annotated locations for NP_777259.1

    Status: PROVISIONAL

    Source sequence(s)
    AB022023
    UniProtKB/Swiss-Prot
    Q27991
    UniProtKB/TrEMBL
    A0A452DIZ9
    Related
    ENSBTAP00070028630.1, ENSBTAT00070047851.1
    Conserved Domains (8) summary
    cd14920
    Location:99 → 771
    MYSc_Myh10; class II myosin heavy chain 10, motor domain
    pfam00063
    Location:87 → 771
    Myosin_head; Myosin head (motor domain)
    pfam01576
    Location:848 → 1928
    Myosin_tail_1; Myosin tail
    pfam02736
    Location:34 → 72
    Myosin_N; Myosin N-terminal SH3-like domain
    pfam11853
    Location:1062 → 1093
    DUF3373; Protein of unknown function (DUF3373)
    cl19511
    Location:1111 → 1222
    DUF2317; Uncharacterized protein conserved in bacteria (DUF2317)
    cl19818
    Location:1645 → 1696
    DUF106; Integral membrane protein DUF106
    cl24005
    Location:1769 → 1867
    DUF2570; Protein of unknown function (DUF2570)

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    28061573..28183702 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_059877752.1 → XP_059733735.1  myosin-10 isoform X1

    UniProtKB/TrEMBL
    A0AAA9RT29, A0AAA9SL38

  2. XM_005220298.5 → XP_005220355.1  myosin-10 isoform X1

    See identical proteins and their annotated locations for XP_005220355.1

    UniProtKB/TrEMBL
    A0AAA9RT29, A0AAA9SL38
    Conserved Domains (8) summary
    cd14920
    Location:99 → 802
    MYSc_Myh10; class II myosin heavy chain 10, motor domain
    pfam00063
    Location:87 → 802
    Myosin_head; Myosin head (motor domain)
    pfam01576
    Location:879 → 1959
    Myosin_tail_1; Myosin tail
    pfam02736
    Location:34 → 72
    Myosin_N; Myosin N-terminal SH3-like domain
    pfam11853
    Location:1093 → 1124
    DUF3373; Protein of unknown function (DUF3373)
    cl19511
    Location:1142 → 1253
    DUF2317; Uncharacterized protein conserved in bacteria (DUF2317)
    cl19818
    Location:1676 → 1727
    DUF106; Integral membrane protein DUF106
    cl24005
    Location:1800 → 1898
    DUF2570; Protein of unknown function (DUF2570)

  3. XM_005220299.5 → XP_005220356.1  myosin-10 isoform X2

    UniProtKB/TrEMBL
    A0AAA9SL38
    Conserved Domains (8) summary
    cd14920
    Location:99 → 792
    MYSc_Myh10; class II myosin heavy chain 10, motor domain
    pfam00063
    Location:87 → 792
    Myosin_head; Myosin head (motor domain)
    pfam01576
    Location:869 → 1949
    Myosin_tail_1; Myosin tail
    pfam02736
    Location:34 → 72
    Myosin_N; Myosin N-terminal SH3-like domain
    pfam11853
    Location:1083 → 1114
    DUF3373; Protein of unknown function (DUF3373)
    cl19511
    Location:1132 → 1243
    DUF2317; Uncharacterized protein conserved in bacteria (DUF2317)
    cl19818
    Location:1666 → 1717
    DUF106; Integral membrane protein DUF106
    cl24005
    Location:1790 → 1888
    DUF2570; Protein of unknown function (DUF2570)

  4. XM_059877753.1 → XP_059733736.1  myosin-10 isoform X3

    UniProtKB/TrEMBL
    A0A452DIZ9, A0AAF7AA92
    Related
    ENSBTAP00070028602.1, ENSBTAT00070047802.1

  5. XM_005220297.5 → XP_005220354.1  myosin-10 isoform X1

    See identical proteins and their annotated locations for XP_005220354.1

    UniProtKB/TrEMBL
    A0AAA9RT29, A0AAA9SL38
    Related
    ENSBTAP00070028589.1, ENSBTAT00070047780.1
    Conserved Domains (8) summary
    cd14920
    Location:99 → 802
    MYSc_Myh10; class II myosin heavy chain 10, motor domain
    pfam00063
    Location:87 → 802
    Myosin_head; Myosin head (motor domain)
    pfam01576
    Location:879 → 1959
    Myosin_tail_1; Myosin tail
    pfam02736
    Location:34 → 72
    Myosin_N; Myosin N-terminal SH3-like domain
    pfam11853
    Location:1093 → 1124
    DUF3373; Protein of unknown function (DUF3373)
    cl19511
    Location:1142 → 1253
    DUF2317; Uncharacterized protein conserved in bacteria (DUF2317)
    cl19818
    Location:1676 → 1727
    DUF106; Integral membrane protein DUF106
    cl24005
    Location:1800 → 1898
    DUF2570; Protein of unknown function (DUF2570)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q27991.2 GenPept UniProtKB/Swiss-Prot:Q27991

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.