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Tab3 TGF-beta activated kinase 1 (MAP3K7) binding protein 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 317546, updated on 19-Apr-2019

Summary

Official Symbol
Tab3provided by RGD
Official Full Name
TGF-beta activated kinase 1 (MAP3K7) binding protein 3provided by RGD
Primary source
RGD:1594527
See related
Ensembl:ENSRNOG00000003643
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Expression
Biased expression in Spleen (RPKM 46.6), Kidney (RPKM 38.7) and 9 other tissues See more
Orthologs

Genomic context

See Tab3 in Genome Data Viewer
Location:
Xq21
Exon count:
8
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (54035958..54090282)
104 previous assembly Rnor_5.0 (GCF_000001895.4) X NC_005120.3 (54239856..54291761)

Chromosome X - NC_005120.4Genomic Context describing neighboring genes Neighboring gene ferritin, heavy polypeptide-like 17, member E Neighboring gene similar to Xanthine dehydrogenase/oxidase Neighboring gene LRRGT00076-like Neighboring gene replication protein A 14 kDa subunit pseudogene Neighboring gene glycerol kinase

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from BioSystems

General gene information

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
positive regulation of I-kappaB kinase/NF-kappaB signaling IEA
Inferred from Electronic Annotation
more info
 
positive regulation of I-kappaB kinase/NF-kappaB signaling ISO
Inferred from Sequence Orthology
more info
PubMed 

General protein information

Preferred Names
LOW QUALITY PROTEIN: TGF-beta-activated kinase 1 and MAP3K7-binding protein 3; TGF-beta-activated kinase 1 and MAP3K7-binding protein 3
Names
TGF-beta activated kinase 1 and MAP3K7 binding protein 3

NCBI Reference Sequences (RefSeq)

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005120.4 Reference Rnor_6.0 Primary Assembly

    Range
    54035958..54090282
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003752051.4XP_003752099.1  LOW QUALITY PROTEIN: TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 isoform X1

    UniProtKB/TrEMBL
    F1M1D2
    Related
    ENSRNOP00000004854.7, ENSRNOT00000004854.7
    Conserved Domains (3) summary
    smart00547
    Location:690712
    ZnF_RBZ; Zinc finger domain
    cd14362
    Location:950
    CUE_TAB2_TAB3; CUE domain found in the N-terminal of TGF-beta-activated kinase 1 and MAP3K7-binding proteins TAB2, TAB3 and similar proteins
    sd00029
    Location:690709
    zf-RanBP2; RanBP2-type Zn finger [structural motif]

Alternate Rn_Celera

Genomic

  1. AC_000089.1 Alternate Rn_Celera

    Range
    50603539..50675711
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006227346.2XP_006227408.1  TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 isoform X1

    See identical proteins and their annotated locations for XP_006227408.1

    Conserved Domains (3) summary
    smart00547
    Location:690712
    ZnF_RBZ; Zinc finger domain
    cd14362
    Location:950
    CUE_TAB2_TAB3; CUE domain found in the N-terminal of TGF-beta-activated kinase 1 and MAP3K7-binding proteins TAB2, TAB3 and similar proteins
    sd00029
    Location:690709
    zf-RanBP2; RanBP2-type Zn finger [structural motif]
  2. XM_008758433.2XP_008756655.1  TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 isoform X1

    See identical proteins and their annotated locations for XP_008756655.1

    Conserved Domains (3) summary
    smart00547
    Location:690712
    ZnF_RBZ; Zinc finger domain
    cd14362
    Location:950
    CUE_TAB2_TAB3; CUE domain found in the N-terminal of TGF-beta-activated kinase 1 and MAP3K7-binding proteins TAB2, TAB3 and similar proteins
    sd00029
    Location:690709
    zf-RanBP2; RanBP2-type Zn finger [structural motif]
  3. XM_008758432.2XP_008756654.1  TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 isoform X2

    See identical proteins and their annotated locations for XP_008756654.1

    Conserved Domains (3) summary
    smart00547
    Location:700722
    ZnF_RBZ; Zinc finger domain
    sd00029
    Location:700719
    zf-RanBP2; RanBP2-type Zn finger [structural motif]
    cl21463
    Location:3760
    UBA_like_SF; UBA domain-like superfamily
  4. XM_006227345.2XP_006227407.1  TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 isoform X2

    See identical proteins and their annotated locations for XP_006227407.1

    Conserved Domains (3) summary
    smart00547
    Location:700722
    ZnF_RBZ; Zinc finger domain
    sd00029
    Location:700719
    zf-RanBP2; RanBP2-type Zn finger [structural motif]
    cl21463
    Location:3760
    UBA_like_SF; UBA domain-like superfamily
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