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rsmA 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA [ Thermus thermophilus HB8 ]

Gene ID: 3169411, updated on 12-Dec-2025
Gene symbol
rsmA
Gene description
16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA
Locus tag
TTH_RS00435
Gene type
protein coding
Organism
Thermus thermophilus HB8 (strain: HB8, type-material: type strain of Thermus thermophilus)
Lineage
Bacteria; Thermotogati; Deinococcota; Deinococci; Thermales; Thermaceae; Thermus
Old locus tag
TTHA0083
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Location:
chromosome: 1
Sequence:
Chromosome: 1; NC_006461.1 (82794..83609)

Chromosome 1 - NC_006461.1Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene Rad52/Rad22 family DNA repair protein Neighboring gene metallophosphoesterase Neighboring gene NADH-quinone oxidoreductase subunit A Neighboring gene NuoB/complex I 20 kDa subunit family protein Neighboring gene NADH-quinone oxidoreductase subunit C Neighboring gene NADH dehydrogenase (quinone) subunit D

Genomic Sequence:
NC_006461.1

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Modification of 16S ribosomal RNA by the KsgA methyltransferase restructures the 30S subunit to optimize ribosome function. Demirci H, et al. RNA, 2010 Dec. PMID 20962038, Free PMC Article
  2. Structural rearrangements in the active site of the Thermus thermophilus 16S rRNA methyltransferase KsgA in a binary complex with 5'-methylthioadenosine. Demirci H, et al. J Mol Biol, 2009 May 1. PMID 19285505, Free PMC Article
  3. The DIM1 gene responsible for the conserved m6(2)Am6(2)A dimethylation in the 3'-terminal loop of 18 S rRNA is essential in yeast. Lafontaine D, et al. J Mol Biol, 1994 Aug 19. PMID 8064863

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The KsgA-directed methylations facilitate structural rearrangements in order to establish a functionally optimum subunit conformation during the final stages of ribosome assembly.
    Title: Modification of 16S ribosomal RNA by the KsgA methyltransferase restructures the 30S subunit to optimize ribosome function.
  2. orientation of residues in the substrate-binding site indicates that conformational changes
    Title: Structural rearrangements in the active site of the Thermus thermophilus 16S rRNA methyltransferase KsgA in a binary complex with 5'-methylthioadenosine.
Submit: New GeneRIF Correction
Preferred Names
16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA
WP_011227698.1

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_006461.1 Reference assembly

    Range
    82794..83609
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_011227698.1 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA

    See identical proteins and their annotated locations for WP_011227698.1

    UniProtKB/Swiss-Prot
    Q5SM60
    Conserved Domains (1) summary
    PRK00274
    Location:6 → 268
    ksgA; 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5SM60.1

Gene LinkOut

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Research Materials