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Ir7c Ionotropic receptor 7c [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31692, updated on 6-Jul-2026
Official Symbol
Ir7cprovided by FlyBase
Official Full Name
Ionotropic receptor 7cprovided by FlyBase
Primary source
FLYBASE:FBgn0029966
Locus tag
Dmel_CG15324
See related
AllianceGenome:FB:FBgn0029966
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
7c; CG15324; CT35324; DmelIR7c; Dmel\CG15324; IR7c
Summary
Predicted to enable ligand-gated monoatomic ion channel activity. Predicted to be involved in detection of chemical stimulus. Predicted to be located in membrane. Is expressed in labellar taste bristle; leg taste bristle chemosensory neurons; organism subdivision; and spermatozoon. [provided by Alliance of Genome Resources, Jul 2025]
Orthologs
all
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Try the new Transcripts and proteins table
See Ir7c in Genome Data Viewer
Location:
7C1-7C1; 1-21 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (7874394..7876847)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (7768427..7770880)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Ionotropic receptor 7b Neighboring gene defective chorion Neighboring gene antisense RNA:CR43615 Neighboring gene Ionotropic receptor 7d Neighboring gene Ionotropic receptor 7e

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Functional imaging and connectome analyses reveal organizing principles of taste circuits in Drosophila. Li J, et al. Curr Biol, 2025 May 19. PMID 40334663
  2. Taste cells expressing Ionotropic Receptor 94e reciprocally impact feeding and egg laying in Drosophila. Guillemin J, et al. Cell Rep, 2024 Aug 27. PMID 39141516
  3. A molecular mechanism for high salt taste in Drosophila. McDowell SAT, et al. Curr Biol, 2022 Jul 25. PMID 35772408
  4. Mechanisms of lactic acid gustatory attraction in Drosophila. Stanley M, et al. Curr Biol, 2021 Aug 23. PMID 34197729
  5. Ionotropic receptors mediate arachidic acid perception and food avoidance behavior in Drosophila melanogaster. Pradhan RN, et al. Mol Cells, 2025 Dec. PMID 41192484, Free PMC Article

See all (37) citations in PubMed

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ligand-gated monoatomic ion channel activity IEA
Inferred from Electronic Annotation
more info
  
enables ligand-gated monoatomic ion channel activity ISM
Inferred from Sequence Model
more info
 PubMed 
Process Evidence Code Pubs
involved_in detection of chemical stimulus ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
involved_in detection of chemical stimulus involved in sensory perception IEA
Inferred from Electronic Annotation
more info
  
involved_in monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane ISM
Inferred from Sequence Model
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
ionotropic receptor 7c
Names
CG15324-PA
CG15324-PB
Ir7c-PA
Ir7c-PB

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    7874394..7876847
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001258643.1 → NP_001245572.1  ionotropic receptor 7c, isoform B

    See identical proteins and their annotated locations for NP_001245572.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W3P2
    Conserved Domains (2) summary
    smart00918
    Location:225 → 287
    Lig_chan-Glu_bd; Ligated ion channel L-glutamate- and glycine-binding site
    pfam00060
    Location:343 → 593
    Lig_chan; Ligand-gated ion channel

  2. NM_132183.2 → NP_572411.1  ionotropic receptor 7c, isoform A

    See identical proteins and their annotated locations for NP_572411.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W3P2
    Related
    FBpp0071043
    Conserved Domains (2) summary
    smart00918
    Location:225 → 287
    Lig_chan-Glu_bd; Ligated ion channel L-glutamate- and glycine-binding site
    pfam00060
    Location:343 → 593
    Lig_chan; Ligand-gated ion channel
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9W3P2 Q9W3P2

Gene LinkOut

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