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Inx6 Innexin 6 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31645, updated on 6-Jul-2026
Official Symbol
Inx6provided by FlyBase
Official Full Name
Innexin 6provided by FlyBase
Primary source
FLYBASE:FBgn0027107
Locus tag
Dmel_CG17063
See related
AllianceGenome:FB:FBgn0027107
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG17063; Dm-inx6; Dmel\CG17063; FBpp0077031; inx-6; inx6; prp6
Summary
Predicted to enable gap junction channel activity. Involved in medium-term memory. Located in gap junction. Is expressed in adult brain; fan-shaped body; and pedunculus of adult mushroom body. [provided by Alliance of Genome Resources, Jul 2025]
Orthologs
all
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Try the new Transcripts and proteins table
See Inx6 in Genome Data Viewer
Location:
19C1-19C1; 1-64 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (20267821..20269769, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (20138847..20140795, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45504 Neighboring gene long non-coding RNA:CR45505

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Acute control of the sleep switch in Drosophila reveals a role for gap junctions in regulating behavioral responsiveness. Troup M, et al. Elife, 2018 Aug 15. PMID 30109983, Free PMC Article
  2. Recent findings in evolution and function of insect innexins. Hasegawa DK, et al. FEBS Lett, 2014 Apr 17. PMID 24631533
  3. Drosophila has several genes for gap junction proteins. Curtin KD, et al. Gene, 1999 May 31. PMID 10352230
  4. Evolutionary diversification of insect innexins. Hughes AL. J Insect Sci, 2014. PMID 25502029, Free PMC Article
  5. Evolutionary analyses of gap junction protein families. Abascal F, et al. Biochim Biophys Acta, 2013 Jan. PMID 22366062

See all (43) citations in PubMed

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables gap junction channel activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in intercellular transport ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in medium-term memory IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in phototransduction IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in gap junction IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in gap junction IDA
Inferred from Direct Assay
more info
 PubMed 
located_in gap junction IEA
Inferred from Electronic Annotation
more info
  
located_in membrane NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
innexin 6
Names
CG17063-PA
Inx6-PA
inx6
pas related protein 6

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    20267821..20269769 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_132146.2 → NP_572374.1  innexin 6

    See identical proteins and their annotated locations for NP_572374.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9UA15, Q9VR82
    Related
    FBpp0077031
    Conserved Domains (1) summary
    pfam00876
    Location:21 → 389
    Innexin; Innexin
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VR82.1 Q9VR82

Gene LinkOut

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