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Prss40 protease, serine, 40 [ Rattus norvegicus (Norway rat) ]

Gene ID: 316318, updated on 24-Apr-2022

Summary

Official Symbol
Prss40provided by RGD
Official Full Name
protease, serine, 40provided by RGD
Primary source
RGD:1561330
See related
Ensembl:ENSRNOG00000014001 AllianceGenome:RGD:1561330
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Tesp2; RGD1561330
Summary
Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward (RPKM 37.2) See more
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Genomic context

See Prss40 in Genome Data Viewer
Location:
9q21
Exon count:
5
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (36762170..36770979, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (41061116..41069929, complement)

Chromosome 9 - NC_051344.1Genomic Context describing neighboring genes Neighboring gene protease, serine, 39 Neighboring gene small nucleolar RNA SNORA51 Neighboring gene cripto, FRL-1, cryptic family 1 Neighboring gene RCC1 and BTB domain containing protein 1, pseudogene 1 Neighboring gene APC membrane recruitment protein 3 Neighboring gene thymosin beta-10-like Neighboring gene ribosomal protein lateral stalk subunit P1, pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables serine-type endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in proteolysis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
serine protease 40
Names
testicular serine protease 2
NP_001101679.1
XP_038939487.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108209.1NP_001101679.1  serine protease 40 precursor

    See identical proteins and their annotated locations for NP_001101679.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473965
    UniProtKB/TrEMBL
    D3ZR46
    Related
    ENSRNOP00000018758.5, ENSRNOT00000018758.6
    Conserved Domains (2) summary
    smart00020
    Location:70310
    Tryp_SPc; Trypsin-like serine protease
    cd00190
    Location:71313
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051344.1 Reference mRatBN7.2 Primary Assembly

    Range
    36762170..36770979 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039083559.1XP_038939487.1  serine protease 40 isoform X1

    Conserved Domains (1) summary
    cd00190
    Location:2199
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...