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Polh DNA polymerase eta [ Rattus norvegicus (Norway rat) ]

Gene ID: 316235, updated on 23-May-2018
Official Symbol
Polhprovided by RGD
Official Full Name
DNA polymerase etaprovided by RGD
Primary source
RGD:1309893
See related
Ensembl:ENSRNOG00000019195
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Expression
Biased expression in Thymus (RPKM 80.5), Spleen (RPKM 56.2) and 9 other tissues See more
Orthologs
See Polh in Genome Data Viewer
Location:
9q12
Exon count:
11
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (17163354..17198006)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 9 NC_005108.3 (16059843..16094495)

Chromosome 9 - NC_005108.4Genomic Context describing neighboring genes Neighboring gene RNA polymerase I and III subunit C Neighboring gene exportin 5 Neighboring gene activated RNA polymerase II transcriptional coactivator p15 pseudogene Neighboring gene GTP binding protein 2 Neighboring gene ribosomal protein S2, pseudogene 6

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
DNA-directed DNA polymerase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
DNA-directed DNA polymerase activity IEA
Inferred from Electronic Annotation
more info
 
DNA-directed DNA polymerase activity ISO
Inferred from Sequence Orthology
more info
 
damaged DNA binding IEA
Inferred from Electronic Annotation
more info
 
molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
DNA synthesis involved in DNA repair IEA
Inferred from Electronic Annotation
more info
 
DNA synthesis involved in DNA repair ISO
Inferred from Sequence Orthology
more info
 
biological_process ND
No biological Data available
more info
 
cellular response to UV-C IEA
Inferred from Electronic Annotation
more info
 
cellular response to UV-C ISO
Inferred from Sequence Orthology
more info
 
error-prone translesion synthesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
postreplication repair IEA
Inferred from Electronic Annotation
more info
 
postreplication repair ISO
Inferred from Sequence Orthology
more info
 
pyrimidine dimer repair IEA
Inferred from Electronic Annotation
more info
 
pyrimidine dimer repair ISO
Inferred from Sequence Orthology
more info
 
response to UV-C ISO
Inferred from Sequence Orthology
more info
 
response to radiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
cellular_component ND
No biological Data available
more info
 
cytosol IEA
Inferred from Electronic Annotation
more info
 
cytosol ISO
Inferred from Sequence Orthology
more info
 
nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
replication fork IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
site of double-strand break IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Preferred Names
DNA polymerase eta
Names
DNA-directed DNA polymerase eta
polymerase (DNA directed), eta (RAD 30 related)
polymerase (DNA) eta
NP_001101674.1
XP_006244599.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108204.1NP_001101674.1  DNA polymerase eta

    See identical proteins and their annotated locations for NP_001101674.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473987
    UniProtKB/TrEMBL
    D4ADZ0
    Related
    ENSRNOP00000026049.2, ENSRNOT00000026049.3
    Conserved Domains (2) summary
    cd01702
    Location:10427
    PolY_Pol_eta; DNA Polymerase eta
    COG0389
    Location:8325
    DinP; Nucleotidyltransferase/DNA polymerase involved in DNA repair [Replication, recombination and repair]

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005108.4 Reference Rnor_6.0 Primary Assembly

    Range
    17163354..17198006
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006244537.1XP_006244599.1  DNA polymerase eta isoform X1

    Conserved Domains (2) summary
    COG0389
    Location:44188
    DinP; Nucleotidyltransferase/DNA polymerase involved in DNA repair [Replication, recombination and repair]
    cl12025
    Location:52290
    PolY; Y-family of DNA polymerases

Alternate Rn_Celera

Genomic

  1. AC_000077.1 Alternate Rn_Celera

    Range
    12525667..12559453
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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