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Klc4 kinesin light chain 4 [ Rattus norvegicus (Norway rat) ]

Gene ID: 316226, updated on 30-May-2026
Official Symbol
Klc4provided by RGD
Official Full Name
kinesin light chain 4provided by RGD
Primary source
RGD:1306555
See related
Ensembl:ENSRNOG00000018168 AllianceGenome:RGD:1306555
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Knsl8; 1200014p03rik
Summary
Predicted to enable kinesin binding activity. Predicted to be involved in microtubule-based movement. Predicted to be located in microtubule. Predicted to be part of kinesin complex. Predicted to be active in cytoplasm. Orthologous to human KLC4 (kinesin light chain 4). [provided by Alliance of Genome Resources, Jul 2025]
Expression
Biased expression in Kidney (RPKM 291.5), Heart (RPKM 143.6) and 9 other tissues See more
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See Klc4 in Genome Data Viewer
Location:
9q12
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (21834765..21848676)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (14337164..14351075)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (16647577..16661463)

Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene cullin 7 Neighboring gene mitochondrial ribosomal protein L2 Neighboring gene protein tyrosine kinase 7 Neighboring gene uncharacterized LOC120094784

Go to nucleotide: Graphics FASTA GenBank

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Clone Names

  • MGC94745

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables kinesin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in microtubule-based movement IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
part_of kinesin complex IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
kinesin light chain 4
Names
KLC 4
kinesin-like 8
kinesin-like protein 8

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001009601.2 → NP_001009601.1  kinesin light chain 4

    See identical proteins and their annotated locations for NP_001009601.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000009
    UniProtKB/Swiss-Prot
    Q5PQM2
    UniProtKB/TrEMBL
    A6JIQ2
    Related
    ENSRNOP00000038363.3, ENSRNOT00000031625.5
    Conserved Domains (3) summary
    TIGR02168
    Location:33 → 148
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    sd00006
    Location:295 → 323
    TPR; TPR repeat [structural motif]
    pfam13424
    Location:294 → 369
    TPR_12; Tetratricopeptide repeat

  2. NM_001432593.1 → NP_001419522.1  kinesin light chain 4

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000009
    UniProtKB/Swiss-Prot
    Q5PQM2
    UniProtKB/TrEMBL
    A6JIQ2

  3. NM_001432594.1 → NP_001419523.1  kinesin light chain 4

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000009
    UniProtKB/Swiss-Prot
    Q5PQM2
    UniProtKB/TrEMBL
    A6JIQ2

  4. NM_001432595.1 → NP_001419524.1  kinesin light chain 4

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000009
    UniProtKB/Swiss-Prot
    Q5PQM2
    UniProtKB/TrEMBL
    A6JIQ2

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086027.1 Reference GRCr8

    Range
    21834765..21848676
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039083506.1 → XP_038939434.1  kinesin light chain 4 isoform X2

    Conserved Domains (2) summary
    TIGR02168
    Location:33 → 148
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam13424
    Location:210 → 264
    TPR_12; Tetratricopeptide repeat

  2. XM_006244516.5 → XP_006244578.1  

    Conserved Domains (3) summary
    TIGR02168
    Location:33 → 148
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    sd00006
    Location:295 → 323
    TPR; TPR repeat [structural motif]
    pfam13424
    Location:294 → 369
    TPR_12; Tetratricopeptide repeat

  3. XM_006244517.4 → XP_006244579.1  

    Conserved Domains (3) summary
    TIGR02168
    Location:33 → 148
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    sd00006
    Location:295 → 323
    TPR; TPR repeat [structural motif]
    pfam13424
    Location:294 → 369
    TPR_12; Tetratricopeptide repeat
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5PQM2.1 GenPept UniProtKB/Swiss-Prot:Q5PQM2

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