Cmtm6 CKLF-like MARVEL transmembrane domain containing 6 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Cmtm6provided by RGD
Official Full Name: CKLF-like MARVEL transmembrane domain containing 6provided by RGD
Primary source: RGD:1307765
See related: Ensembl:ENSRNOG00000010951 AllianceGenome:RGD:1307765
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Da2-17; Cklfsf6; LRRGT00102
Summary: Predicted to be involved in endocytic recycling; protein transport; and regulation of protein stability. Predicted to be located in early endosome membrane; plasma membrane; and recycling endosome membrane. Predicted to be active in membrane. Orthologous to human CMTM6 (CKLF like MARVEL transmembrane domain containing 6). [provided by Alliance of Genome Resources, Jul 2025]
Expression: Biased expression in Lung (RPKM 378.0), Kidney (RPKM 364.7) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 8q32

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	8	NC_086026.1 (123301131..123319230)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	8	NC_051343.1 (114422934..114441034)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	8	NC_005107.4 (122789208..122807560)

Chromosome 8 - NC_086026.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH129085 (e-PCR)
- UniSTS:212393

RH137069 (e-PCR)
- UniSTS:212393

D8Rat200 (e-PCR), detects polymorphism
- UniSTS:228267

RH127860 (e-PCR)
- UniSTS:211170

Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in endocytic recycling	ISO Inferred from Sequence Orthology more info
involved_in protein transport	ISO Inferred from Sequence Orthology more info
involved_in regulation of protein stability	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in early endosome membrane	ISO Inferred from Sequence Orthology more info
is_active_in membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	ISO Inferred from Sequence Orthology more info
located_in recycling endosome membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: CKLF-like MARVEL transmembrane domain-containing protein 6

Names: chemokine-like factor super family 6; chemokine-like factor superfamily 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.