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Ppp2r1b protein phosphatase 2 scaffold subunit A beta [ Rattus norvegicus (Norway rat) ]

Gene ID: 315648, updated on 5-Sep-2020

Summary

Official Symbol
Ppp2r1bprovided by RGD
Official Full Name
protein phosphatase 2 scaffold subunit A betaprovided by RGD
Primary source
RGD:1304764
See related
Ensembl:ENSRNOG00000010922
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Expression
Biased expression in Kidney (RPKM 166.4), Spleen (RPKM 86.5) and 9 other tissues See more
Orthologs

Genomic context

See Ppp2r1b in Genome Data Viewer
Location:
8q23
Exon count:
17
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (55279278..55311768)
106 current Rn_Celera (GCF_000002265.2) 8 AC_000076.1 (50743113..50764139)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 8 NC_005107.3 (53865408..53907521)

Chromosome 8 - NC_005107.4Genomic Context describing neighboring genes Neighboring gene ALG9, alpha-1,2-mannosyltransferase Neighboring gene 60S ribosomal protein L27a-like Neighboring gene salt-inducible kinase 2 Neighboring gene BTG anti-proliferation factor 4 Neighboring gene layilin Neighboring gene HOATZ cilia and flagella associated protein

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
molecular_function ND
No biological Data available
more info
 
protein phosphatase regulator activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
contributes_to protein serine/threonine phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
apoptotic process involved in morphogenesis ISO
Inferred from Sequence Orthology
more info
 
biological_process ND
No biological Data available
more info
 
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand ISO
Inferred from Sequence Orthology
more info
 
protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
 
regulation of phosphoprotein phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cellular_component ND
No biological Data available
more info
 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
glutamatergic synapse ISO
Inferred from Sequence Orthology
more info
 
membrane raft ISO
Inferred from Sequence Orthology
more info
 
protein phosphatase type 2A complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein serine/threonine phosphatase complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
synapse ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform
Names
protein phosphatase 2, regulatory subunit A, beta
NP_001020589.1
XP_017451115.1
XP_017451116.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001025418.1NP_001020589.1  serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

    See identical proteins and their annotated locations for NP_001020589.1

    Status: PROVISIONAL

    Source sequence(s)
    BC098007
    UniProtKB/Swiss-Prot
    Q4QQT4
    Related
    ENSRNOP00000059428.1, ENSRNOT00000064290.2
    Conserved Domains (4) summary
    pfam02985
    Location:295325
    HEAT; HEAT repeat
    pfam13513
    Location:191240
    HEAT_EZ; HEAT-like repeat
    pfam13646
    Location:217315
    HEAT_2; HEAT repeats
    sd00044
    Location:257281
    HEAT; HEAT repeat [structural motif]

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005107.4 Reference Rnor_6.0 Primary Assembly

    Range
    55279278..55311768
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017595627.1XP_017451116.1  serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X2

  2. XM_017595626.1XP_017451115.1  serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X1

Alternate Rn_Celera

Genomic

  1. AC_000076.1 Alternate Rn_Celera

    Range
    50743113..50764139
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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