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Espl1 extra spindle pole bodies like 1, separase [ Rattus norvegicus (Norway rat) ]

Gene ID: 315330, updated on 13-Aug-2019

Summary

Official Symbol
Espl1provided by RGD
Official Full Name
extra spindle pole bodies like 1, separaseprovided by RGD
Primary source
RGD:1306266
See related
Ensembl:ENSRNOG00000012835
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Expression
Biased expression in Thymus (RPKM 55.3), Testes (RPKM 49.5) and 8 other tissues See more
Orthologs

Genomic context

See Espl1 in Genome Data Viewer
Location:
7q36
Exon count:
31
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (143896890..143923868)
106 current Rn_Celera (GCF_000002265.2) 7 AC_000075.1 (129857507..129884392)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 7 NC_005106.3 (141692925..141719617) , (143153049..143161944)

Chromosome 7 - NC_005106.4Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102552775 Neighboring gene major facilitator superfamily domain containing 5 Neighboring gene prefoldin subunit 5 Neighboring gene melanocyte proliferating gene 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
cysteine-type endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cysteine-type peptidase activity ISO
Inferred from Sequence Orthology
more info
PubMed 
peptidase activity ISO
Inferred from Sequence Orthology
more info
PubMed 
Process Evidence Code Pubs
chromosome segregation ISO
Inferred from Sequence Orthology
more info
PubMed 
homologous chromosome segregation IEA
Inferred from Electronic Annotation
more info
 
homologous chromosome segregation ISO
Inferred from Sequence Orthology
more info
PubMed 
meiosis I ISO
Inferred from Sequence Orthology
more info
PubMed 
meiotic chromosome separation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
meiotic spindle organization IEA
Inferred from Electronic Annotation
more info
 
meiotic spindle organization ISO
Inferred from Sequence Orthology
more info
PubMed 
mitotic cell cycle ISO
Inferred from Sequence Orthology
more info
PubMed 
mitotic sister chromatid segregation IEA
Inferred from Electronic Annotation
more info
 
mitotic sister chromatid segregation ISO
Inferred from Sequence Orthology
more info
PubMed 
proteolysis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
centrosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
centrosome ISO
Inferred from Sequence Orthology
more info
PubMed 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitotic spindle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
separin
Names
extra spindle pole bodies 1, separase
extra spindle pole bodies homolog 1
extra spindle poles like 1
NP_001164073.1
XP_006242522.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001170602.1NP_001164073.1  separin

    See identical proteins and their annotated locations for NP_001164073.1

    Status: VALIDATED

    Source sequence(s)
    AC097309
    UniProtKB/TrEMBL
    D3ZDT7
    Related
    ENSRNOP00000017314.6, ENSRNOT00000017314.6
    Conserved Domains (1) summary
    pfam03568
    Location:17092056
    Peptidase_C50; Peptidase family C50

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005106.4 Reference Rnor_6.0 Primary Assembly

    Range
    143896890..143923868
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006242460.3XP_006242522.1  separin isoform X1

    See identical proteins and their annotated locations for XP_006242522.1

    UniProtKB/TrEMBL
    D3ZDT7
    Conserved Domains (1) summary
    pfam03568
    Location:17092056
    Peptidase_C50; Peptidase family C50

Alternate Rn_Celera

Genomic

  1. AC_000075.1 Alternate Rn_Celera

    Range
    129857507..129884392
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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