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Mcm3 Minichromosome maintenance 3 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31449, updated on 10-Oct-2019

Summary

Official Symbol
Mcm3provided by FlyBase
Official Full Name
Minichromosome maintenance 3provided by FlyBase
Primary source
FLYBASE:FBgn0284442
Locus tag
Dmel_CG4206
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG4206; dMcm3; dMCM3; Dmel\CG4206; DmeMCM3; DmMcm3; DmMCM3; mcm3; McM3; MCM3; Mcp-PCR2; PCR2; smu

Genomic context

See Mcm3 in Genome Data Viewer
Location:
4F5-4F5; 1-11 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.26 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (5323855..5326738)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (5217888..5220771)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Something about silencing 10 Neighboring gene RNA-binding protein 4F Neighboring gene uncharacterized protein Neighboring gene XRCC1 Neighboring gene Calcineurin B

Genomic regions, transcripts, and products

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the Mcm3 gene: The Mcm3 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, mosquito, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog.
  • Orthologs

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
contributes_to 3'-5' DNA helicase activity IDA
Inferred from Direct Assay
more info
PubMed 
ATP binding IEA
Inferred from Electronic Annotation
more info
 
DNA replication origin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
single-stranded DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
DNA strand elongation involved in DNA replication IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
double-strand break repair via break-induced replication IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitotic DNA replication initiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mushroom body development IMP
Inferred from Mutant Phenotype
more info
PubMed 
neuroblast proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
pre-replicative complex assembly involved in nuclear cell cycle DNA replication IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
MCM complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
minichromosome maintenance 3
Names
CG4206-PA
CG4206-PB
Mcm3-PA
Mcm3-PB
minichromosome maintenance-PCR2
small mushroom bodies

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    5323855..5326738
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_078493.4NP_511048.2  minichromosome maintenance 3, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_511048.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9XYU1
    Related
    FBpp0070729, FBtr0070762
    Conserved Domains (3) summary
    smart00350
    Location:106648
    MCM; minichromosome maintenance proteins
    pfam14551
    Location:15126
    MCM_N; MCM N-terminal domain
    cl21455
    Location:391449
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  2. NM_001297955.1NP_001284884.1  minichromosome maintenance 3, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001284884.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    X2JAI4
    Related
    FBpp0309417, FBtr0340476
    Conserved Domains (3) summary
    smart00350
    Location:106647
    MCM; minichromosome maintenance proteins
    pfam14551
    Location:15126
    MCM_N; MCM N-terminal domain
    cl21455
    Location:391449
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
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