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Ankrd9 ankyrin repeat domain 9 [ Rattus norvegicus (Norway rat) ]

Gene ID: 314457, updated on 30-May-2026
Official Symbol
Ankrd9provided by RGD
Official Full Name
ankyrin repeat domain 9provided by RGD
Primary source
RGD:1307662
See related
Ensembl:ENSRNOG00000072270 AllianceGenome:RGD:1307662
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in intracellular copper ion homeostasis; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein ubiquitination. Predicted to be located in cytoplasmic vesicle and cytosol. Predicted to be part of Cul5-RING ubiquitin ligase complex. Orthologous to human ANKRD9 (ankyrin repeat domain 9). [provided by Alliance of Genome Resources, Jul 2025]
Expression
Biased expression in Muscle (RPKM 203.4), Testes (RPKM 137.3) and 9 other tissues See more
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See Ankrd9 in Genome Data Viewer
Location:
6q32
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (135827355..135830002, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (130001914..130008792, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (135409698..135412552, complement)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 839 Neighboring gene cyclin-dependent kinase 2-interacting protein Neighboring gene tectonin beta-propeller repeat containing 2 Neighboring gene uncharacterized LOC134479258 Neighboring gene uncharacterized LOC134479478 Neighboring gene REST corepressor 1

Go to nucleotide: Graphics FASTA GenBank

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables ubiquitin-like ligase-substrate adaptor activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in intracellular copper ion homeostasis ISO
Inferred from Sequence Orthology
more info
  
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process ISO
Inferred from Sequence Orthology
more info
  
involved_in protein ubiquitination ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
part_of Cul5-RING ubiquitin ligase complex ISO
Inferred from Sequence Orthology
more info
  
located_in cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasmic vesicle ISO
Inferred from Sequence Orthology
more info
  
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
Preferred Names
ankyrin repeat domain-containing protein 9

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012112.1 → NP_001012112.1  ankyrin repeat domain-containing protein 9

    See identical proteins and their annotated locations for NP_001012112.1

    Status: PROVISIONAL

    Source sequence(s)
    BC079192
    UniProtKB/TrEMBL
    A6KBP4, Q6P755
    Related
    ENSRNOP00000010610.3, ENSRNOT00000010610.7
    Conserved Domains (2) summary
    sd00045
    Location:157 → 188
    ANK; ANK repeat [structural motif]
    pfam13857
    Location:156 → 197
    Ank_5; Ankyrin repeats (many copies)

  2. NM_001443948.1 → NP_001430877.1  ankyrin repeat domain-containing protein 9

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006
    UniProtKB/TrEMBL
    A6KBP4, Q6P755

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    135827355..135830002 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008764937.3 → XP_008763159.1  ankyrin repeat domain-containing protein 9 isoform X1

    See identical proteins and their annotated locations for XP_008763159.1

    UniProtKB/TrEMBL
    A6KBP4, Q6P755
    Related
    ENSRNOP00000111556.1, ENSRNOT00000151841.1
    Conserved Domains (2) summary
    sd00045
    Location:157 → 188
    ANK; ANK repeat [structural motif]
    pfam13857
    Location:156 → 197
    Ank_5; Ankyrin repeats (many copies)

  2. XM_017594189.3 → XP_017449678.1  

    Related
    ENSRNOP00000102296.1, ENSRNOT00000172035.1
    Conserved Domains (2) summary
    sd00045
    Location:157 → 188
    ANK; ANK repeat [structural motif]
    pfam13857
    Location:156 → 197
    Ank_5; Ankyrin repeats (many copies)

  3. XM_039112416.2 → XP_038968344.1  ankyrin repeat domain-containing protein 9 isoform X1

    UniProtKB/TrEMBL
    A6KBP4, Q6P755
    Conserved Domains (2) summary
    sd00045
    Location:157 → 188
    ANK; ANK repeat [structural motif]
    pfam13857
    Location:156 → 197
    Ank_5; Ankyrin repeats (many copies)
Nucleotide Protein Strain
Heading Accession and Version

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