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Tal1 TAL bHLH transcription factor 1, erythroid differentiation factor [ Rattus norvegicus (Norway rat) ]

Gene ID: 313507, updated on 3-Jun-2018
Official Symbol
Tal1provided by RGD
Official Full Name
TAL bHLH transcription factor 1, erythroid differentiation factorprovided by RGD
Primary source
RGD:1306748
See related
Ensembl:ENSRNOG00000025051
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Tal-1
Expression
Biased expression in Spleen (RPKM 222.3), Lung (RPKM 66.0) and 5 other tissues See more
Orthologs
See Tal1 in Genome Data Viewer
Location:
5q35
Exon count:
7
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (133864401..133878604)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 5 NC_005104.3 (137655978..137670144)

Chromosome 5 - NC_005104.4Genomic Context describing neighboring genes Neighboring gene cytidine/uridine monophosphate kinase 1 Neighboring gene STIL, centriolar assembly protein Neighboring gene PDZK1 interacting protein 1 Neighboring gene cytochrome P450, family 4, subfamily x, polypeptide 1

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
contributes_to DNA binding ISO
Inferred from Sequence Orthology
more info
 
DNA-binding transcription factor activity ISO
Inferred from Sequence Orthology
more info
 
E-box binding IEA
Inferred from Electronic Annotation
more info
 
E-box binding ISO
Inferred from Sequence Orthology
more info
 
RNA polymerase II distal enhancer sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
RNA polymerase II distal enhancer sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
RNA polymerase II proximal promoter sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
RNA polymerase II regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
RNA polymerase II transcription factor activity, sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
RNA polymerase II transcription factor binding IEA
Inferred from Electronic Annotation
more info
 
RNA polymerase II transcription factor binding ISO
Inferred from Sequence Orthology
more info
 
chromatin binding IEA
Inferred from Electronic Annotation
more info
 
chromatin binding ISO
Inferred from Sequence Orthology
more info
 
enzyme binding ISO
Inferred from Sequence Orthology
more info
 
histone deacetylase binding IEA
Inferred from Electronic Annotation
more info
 
histone deacetylase binding ISO
Inferred from Sequence Orthology
more info
 
molecular_function ND
No biological Data available
more info
 
protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
 
protein heterodimerization activity ISO
Inferred from Sequence Orthology
more info
 
transcription regulatory region DNA binding ISO
Inferred from Sequence Orthology
more info
 
transcription regulatory region sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
angiogenesis IEA
Inferred from Electronic Annotation
more info
 
angiogenesis ISO
Inferred from Sequence Orthology
more info
 
astrocyte fate commitment IEA
Inferred from Electronic Annotation
more info
 
astrocyte fate commitment ISO
Inferred from Sequence Orthology
more info
 
basophil differentiation IEA
Inferred from Electronic Annotation
more info
 
basophil differentiation ISO
Inferred from Sequence Orthology
more info
 
biological_process ND
No biological Data available
more info
 
cell fate commitment ISO
Inferred from Sequence Orthology
more info
 
definitive hemopoiesis IEA
Inferred from Electronic Annotation
more info
 
definitive hemopoiesis ISO
Inferred from Sequence Orthology
more info
 
embryonic hemopoiesis ISO
Inferred from Sequence Orthology
more info
 
erythrocyte differentiation ISO
Inferred from Sequence Orthology
more info
 
erythrocyte maturation IEA
Inferred from Electronic Annotation
more info
 
erythrocyte maturation ISO
Inferred from Sequence Orthology
more info
 
generation of neurons ISO
Inferred from Sequence Orthology
more info
 
hemangioblast cell differentiation IEA
Inferred from Electronic Annotation
more info
 
hemangioblast cell differentiation ISO
Inferred from Sequence Orthology
more info
 
hematopoietic stem cell differentiation IEA
Inferred from Electronic Annotation
more info
 
hematopoietic stem cell differentiation ISO
Inferred from Sequence Orthology
more info
 
hemopoiesis ISO
Inferred from Sequence Orthology
more info
 
locomotory behavior IEA
Inferred from Electronic Annotation
more info
 
locomotory behavior ISO
Inferred from Sequence Orthology
more info
 
megakaryocyte development IEA
Inferred from Electronic Annotation
more info
 
megakaryocyte development ISO
Inferred from Sequence Orthology
more info
 
megakaryocyte differentiation ISO
Inferred from Sequence Orthology
more info
 
myeloid cell differentiation ISO
Inferred from Sequence Orthology
more info
 
negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
negative regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
neuron differentiation ISO
Inferred from Sequence Orthology
more info
 
platelet formation IEA
Inferred from Electronic Annotation
more info
 
platelet formation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cell division IEA
Inferred from Electronic Annotation
more info
 
positive regulation of cell division ISO
Inferred from Sequence Orthology
more info
 
positive regulation of chromatin assembly or disassembly IEA
Inferred from Electronic Annotation
more info
 
positive regulation of chromatin assembly or disassembly ISO
Inferred from Sequence Orthology
more info
 
positive regulation of erythrocyte differentiation IEA
Inferred from Electronic Annotation
more info
 
positive regulation of erythrocyte differentiation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
 
positive regulation of mitotic cell cycle ISO
Inferred from Sequence Orthology
more info
 
positive regulation of protein complex assembly IEA
Inferred from Electronic Annotation
more info
 
positive regulation of protein complex assembly ISO
Inferred from Sequence Orthology
more info
 
positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
positive regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
 
regulation of cell proliferation IEA
Inferred from Electronic Annotation
more info
 
regulation of cell proliferation ISO
Inferred from Sequence Orthology
more info
 
regulation of mast cell differentiation IEA
Inferred from Electronic Annotation
more info
 
regulation of mast cell differentiation ISO
Inferred from Sequence Orthology
more info
 
regulation of myeloid cell differentiation ISO
Inferred from Sequence Orthology
more info
 
regulation of stem cell population maintenance IEA
Inferred from Electronic Annotation
more info
 
regulation of stem cell population maintenance ISO
Inferred from Sequence Orthology
more info
 
regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
spinal cord association neuron differentiation IEA
Inferred from Electronic Annotation
more info
 
spinal cord association neuron differentiation ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
Lsd1/2 complex IEA
Inferred from Electronic Annotation
more info
 
colocalizes_with Lsd1/2 complex ISO
Inferred from Sequence Orthology
more info
 
cellular_component ND
No biological Data available
more info
 
histone deacetylase complex IEA
Inferred from Electronic Annotation
more info
 
colocalizes_with histone deacetylase complex ISO
Inferred from Sequence Orthology
more info
 
nuclear chromatin IEA
Inferred from Electronic Annotation
more info
 
nuclear chromatin ISO
Inferred from Sequence Orthology
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 
protein-containing complex ISO
Inferred from Sequence Orthology
more info
 
transcription factor complex IEA
Inferred from Electronic Annotation
more info
 
transcription factor complex ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
T-cell acute lymphocytic leukemia protein 1
Names
T-cell acute lymphocytic leukemia 1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107958.2NP_001101428.2  T-cell acute lymphocytic leukemia protein 1

    See identical proteins and their annotated locations for NP_001101428.2

    Status: VALIDATED

    Source sequence(s)
    AABR07049701
    UniProtKB/TrEMBL
    D3Z921
    Related
    ENSRNOP00000034958.5, ENSRNOT00000035409.5
    Conserved Domains (1) summary
    smart00353
    Location:193243
    HLH; helix loop helix domain

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005104.4 Reference Rnor_6.0 Primary Assembly

    Range
    133864401..133878604
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006238618.3XP_006238680.1  T-cell acute lymphocytic leukemia protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006238680.1

    UniProtKB/TrEMBL
    D3Z921
    Conserved Domains (1) summary
    smart00353
    Location:193243
    HLH; helix loop helix domain
  2. XM_006238615.3XP_006238677.1  T-cell acute lymphocytic leukemia protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006238677.1

    UniProtKB/TrEMBL
    D3Z921
    Conserved Domains (1) summary
    smart00353
    Location:193243
    HLH; helix loop helix domain
  3. XM_008763967.1XP_008762189.1  T-cell acute lymphocytic leukemia protein 1 isoform X1

    See identical proteins and their annotated locations for XP_008762189.1

    UniProtKB/TrEMBL
    D3Z921
    Related
    ENSRNOP00000071897.1, ENSRNOT00000091977.1
    Conserved Domains (1) summary
    smart00353
    Location:193243
    HLH; helix loop helix domain
  4. XM_006238617.1XP_006238679.1  T-cell acute lymphocytic leukemia protein 1 isoform X1

    See identical proteins and their annotated locations for XP_006238679.1

    UniProtKB/TrEMBL
    D3Z921
    Conserved Domains (1) summary
    smart00353
    Location:193243
    HLH; helix loop helix domain

Alternate Rn_Celera

Genomic

  1. AC_000073.1 Alternate Rn_Celera

    Range
    127232703..127245971
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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