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Lrig1 leucine-rich repeats and immunoglobulin-like domains 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 312574, updated on 12-Aug-2018

Summary

Official Symbol
Lrig1provided by RGD
Official Full Name
leucine-rich repeats and immunoglobulin-like domains 1provided by RGD
Primary source
RGD:1306788
See related
Ensembl:ENSRNOG00000012952
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Expression
Biased expression in Thymus (RPKM 256.3), Muscle (RPKM 152.5) and 9 other tissues See more
Orthologs

Genomic context

See Lrig1 in Genome Data Viewer
Location:
4q34
Exon count:
20
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (126615998..126717434, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 4 NC_005103.3 (191129832..191231014, complement)

Chromosome 4 - NC_005103.4Genomic Context describing neighboring genes Neighboring gene hypothetical LOC100362876 Neighboring gene solute carrier family 25 member 26 Neighboring gene uncharacterized LOC108350731 Neighboring gene uncharacterized LOC108350732

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
hair cycle process IEA
Inferred from Electronic Annotation
more info
 
hair cycle process ISO
Inferred from Sequence Orthology
more info
 
innervation IEA
Inferred from Electronic Annotation
more info
 
innervation ISO
Inferred from Sequence Orthology
more info
 
otolith morphogenesis IEA
Inferred from Electronic Annotation
more info
 
otolith morphogenesis ISO
Inferred from Sequence Orthology
more info
 
sensory perception of sound IEA
Inferred from Electronic Annotation
more info
 
sensory perception of sound ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
extracellular matrix IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
leucine-rich repeats and immunoglobulin-like domains protein 1

NCBI Reference Sequences (RefSeq)

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005103.4 Reference Rnor_6.0 Primary Assembly

    Range
    126615998..126717434 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_232237.9XP_232237.6  leucine-rich repeats and immunoglobulin-like domains protein 1 isoform X1

    See identical proteins and their annotated locations for XP_232237.6

    Related
    ENSRNOP00000017384.7, ENSRNOT00000017384.8
    Conserved Domains (9) summary
    cd00096
    Location:517591
    Ig; Immunoglobulin domain
    cd05763
    Location:621695
    Ig_1; Subgroup of the immunoglobulin (Ig) superfamily
    smart00408
    Location:712775
    IGc2; Immunoglobulin C-2 Type
    smart00082
    Location:447495
    LRRCT; Leucine rich repeat C-terminal domain
    cd00116
    Location:138421
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    pfam07679
    Location:604694
    I-set; Immunoglobulin I-set domain
    sd00033
    Location:146169
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12799
    Location:76115
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:313372
    LRR_8; Leucine rich repeat
  2. XM_008763142.2XP_008761364.1  leucine-rich repeats and immunoglobulin-like domains protein 1 isoform X2

    See identical proteins and their annotated locations for XP_008761364.1

    Related
    ENSRNOP00000066785.2, ENSRNOT00000072624.2
    Conserved Domains (9) summary
    cd05763
    Location:575649
    Ig_1; Subgroup of the immunoglobulin (Ig) superfamily
    smart00408
    Location:666729
    IGc2; Immunoglobulin C-2 Type
    smart00082
    Location:401449
    LRRCT; Leucine rich repeat C-terminal domain
    cd00116
    Location:92375
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    pfam07679
    Location:558648
    I-set; Immunoglobulin I-set domain
    sd00033
    Location:100123
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12799
    Location:365398
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:267326
    LRR_8; Leucine rich repeat
    pfam13927
    Location:453540
    Ig_3; Immunoglobulin domain

Alternate Rn_Celera

Genomic

  1. AC_000072.1 Alternate Rn_Celera

    Range
    116039860..116139967 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001076882.3XP_001076882.1  leucine-rich repeats and immunoglobulin-like domains protein 1 isoform X3

    See identical proteins and their annotated locations for XP_001076882.1

    Conserved Domains (9) summary
    cd00096
    Location:517591
    Ig; Immunoglobulin domain
    cd05763
    Location:621695
    Ig_1; Subgroup of the immunoglobulin (Ig) superfamily
    smart00408
    Location:712775
    IGc2; Immunoglobulin C-2 Type
    smart00082
    Location:447495
    LRRCT; Leucine rich repeat C-terminal domain
    cd00116
    Location:138421
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    pfam07679
    Location:604694
    I-set; Immunoglobulin I-set domain
    sd00033
    Location:146169
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12799
    Location:76115
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:313372
    LRR_8; Leucine rich repeat
  2. XM_008775797.2XP_008774019.1  leucine-rich repeats and immunoglobulin-like domains protein 1 isoform X4

    See identical proteins and their annotated locations for XP_008774019.1

    Conserved Domains (9) summary
    cd05763
    Location:575649
    Ig_1; Subgroup of the immunoglobulin (Ig) superfamily
    smart00408
    Location:666729
    IGc2; Immunoglobulin C-2 Type
    smart00082
    Location:401449
    LRRCT; Leucine rich repeat C-terminal domain
    cd00116
    Location:92375
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    pfam07679
    Location:558648
    I-set; Immunoglobulin I-set domain
    sd00033
    Location:100123
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12799
    Location:365398
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:267326
    LRR_8; Leucine rich repeat
    pfam13927
    Location:453540
    Ig_3; Immunoglobulin domain
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