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per period [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31251, updated on 8-Jun-2019

Summary

Official Symbol
perprovided by FlyBase
Official Full Name
periodprovided by FlyBase
Primary source
FLYBASE:FBgn0003068
Locus tag
Dmel_CG2647
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG2647; Clk; clk-6; Dmel\CG2647; dmper; dper; dPER; EG:155E2.4; mel_per; Per; PER; Per-2

Genomic context

See per in Genome Data Viewer
Location:
3B1-3B2; 1-1.5 cM
Exon count:
8
Annotation release Status Assembly Chr Location
Release 6.26 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (2685580..2692780)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (2579613..2586813)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Helix loop helix protein 3B Neighboring gene long non-coding RNA:CR44470 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Paraplegin Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

  • Circadian rhythm - fly, organism-specific biosystem (from KEGG)
    Circadian rhythm - fly, organism-specific biosystemCircadian rhythm is an internal biological clock, which enables to sustain an approximately 24-hour rhythm in the absence of environmental cues. In the fruit fly Drosophila melanogaster, seven genes ...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein heterodimerization activity IPI
Inferred from Physical Interaction
more info
PubMed 
protein heterodimerization activity NAS
Non-traceable Author Statement
more info
PubMed 
protein heterodimerization activity TAS
Traceable Author Statement
more info
PubMed 
protein homodimerization activity IPI
Inferred from Physical Interaction
more info
PubMed 
transcription coregulator activity NAS
Non-traceable Author Statement
more info
PubMed 
transcription corepressor activity TAS
Traceable Author Statement
more info
PubMed 
transcription corepressor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transcription factor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transcription factor binding IPI
Inferred from Physical Interaction
more info
PubMed 
transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
age-dependent response to oxidative stress IMP
Inferred from Mutant Phenotype
more info
PubMed 
behavioral response to cocaine NAS
Non-traceable Author Statement
more info
PubMed 
circadian behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
circadian regulation of gene expression IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
circadian regulation of gene expression IMP
Inferred from Mutant Phenotype
more info
PubMed 
circadian rhythm IMP
Inferred from Mutant Phenotype
more info
PubMed 
circadian rhythm NAS
Non-traceable Author Statement
more info
PubMed 
circadian rhythm TAS
Traceable Author Statement
more info
PubMed 
circadian sleep/wake cycle TAS
Traceable Author Statement
more info
PubMed 
circadian temperature homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
copulation IMP
Inferred from Mutant Phenotype
more info
PubMed 
courtship behavior NAS
Non-traceable Author Statement
more info
PubMed 
determination of adult lifespan IMP
Inferred from Mutant Phenotype
more info
PubMed 
eclosion rhythm IMP
Inferred from Mutant Phenotype
more info
PubMed 
eclosion rhythm NAS
Non-traceable Author Statement
more info
PubMed 
eclosion rhythm TAS
Traceable Author Statement
more info
PubMed 
entrainment of circadian clock IMP
Inferred from Mutant Phenotype
more info
PubMed 
entrainment of circadian clock by photoperiod IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
entrainment of circadian clock by photoperiod IMP
Inferred from Mutant Phenotype
more info
PubMed 
locomotor rhythm IMP
Inferred from Mutant Phenotype
more info
PubMed 
locomotor rhythm NAS
Non-traceable Author Statement
more info
PubMed 
locomotor rhythm TAS
Traceable Author Statement
more info
PubMed 
long-term memory IMP
Inferred from Mutant Phenotype
more info
PubMed 
male courtship behavior, veined wing generated song production NAS
Non-traceable Author Statement
more info
PubMed 
male courtship behavior, veined wing generated song production TAS
Traceable Author Statement
more info
PubMed 
mating behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of transcription by RNA polymerase II NAS
Non-traceable Author Statement
more info
PubMed 
negative regulation of transcription by RNA polymerase II TAS
Traceable Author Statement
more info
PubMed 
negative regulation of transcription regulatory region DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of transcription, DNA-templated IDA
Inferred from Direct Assay
more info
PubMed 
regulation of circadian rhythm IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of circadian sleep/wake cycle, sleep IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of locomotor rhythm IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of protein phosphorylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to light stimulus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
response to light stimulus TAS
Traceable Author Statement
more info
PubMed 
response to oxidative stress IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to temperature stimulus TAS
Traceable Author Statement
more info
PubMed 
rhythmic behavior TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
cell body IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm NAS
Non-traceable Author Statement
more info
PubMed 
cytoplasm TAS
Traceable Author Statement
more info
PubMed 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus NAS
Non-traceable Author Statement
more info
PubMed 
nucleus TAS
Traceable Author Statement
more info
PubMed 

General protein information

Preferred Names
period
Names
CG2647-PA
CG2647-PB
PERIOD
clock
clock-6
dperiod
per-PA
per-PB
period clock protein

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    2685580..2692780
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_080317.2NP_525056.2  period, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_525056.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P07663
    UniProtKB/TrEMBL
    M9PGJ3
    Related
    FBpp0070455, FBtr0070477
    Conserved Domains (3) summary
    cd00130
    Location:388495
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam00989
    Location:238333
    PAS; PAS fold
    pfam14598
    Location:391495
    PAS_11; PAS domain
  2. NM_001272265.1NP_001259194.1  period, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259194.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P07663
    UniProtKB/TrEMBL
    M9PGJ3
    Related
    FBpp0304590, FBtr0332311
    Conserved Domains (3) summary
    cd00130
    Location:388495
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam00989
    Location:238333
    PAS; PAS fold
    pfam14598
    Location:391495
    PAS_11; PAS domain
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