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Nfe2l3 NFE2 like bZIP transcription factor 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 312331, updated on 25-Jan-2022

Summary

Official Symbol
Nfe2l3provided by RGD
Official Full Name
NFE2 like bZIP transcription factor 3provided by RGD
Primary source
RGD:1307730
See related
Ensembl:ENSRNOG00000010886 AllianceGenome:RGD:1307730
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human NFE2L3 (NFE2 like bZIP transcription factor 3). [provided by Alliance of Genome Resources, Nov 2021]
Expression
Biased expression in Thymus (RPKM 224.6), Spleen (RPKM 156.0) and 9 other tissues See more
Orthologs
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Genomic context

See Nfe2l3 in Genome Data Viewer
Location:
4q24
Exon count:
4
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (80506756..80534629)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (81205214..81233068)

Chromosome 4 - NC_051339.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102549423 Neighboring gene uncharacterized LOC120102270 Neighboring gene heterogeneous nuclear ribonucleoprotein A2/B1 Neighboring gene chromobox 3

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Homology

General protein information

Preferred Names
nuclear factor erythroid 2-related factor 3
Names
nuclear factor, erythroid 2-like 3
nuclear factor, erythroid derived 2, like 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001305047.1NP_001291976.1  nuclear factor erythroid 2-related factor 3 precursor

    Status: VALIDATED

    Source sequence(s)
    DY310098, JACYVU010000142
    UniProtKB/TrEMBL
    D4A7S7
    Related
    ENSRNOP00000014826.4, ENSRNOT00000014826.5
    Conserved Domains (1) summary
    cd14720
    Location:526593
    bZIP_NFE2-like; Basic leucine zipper (bZIP) domain of Nuclear Factor, Erythroid-derived 2 (NFE2) and similar proteins: a DNA-binding and dimerization domain

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051339.1 Reference mRatBN7.2 Primary Assembly

    Range
    80506756..80534629
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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