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Luc7l2 LUC7-like 2 pre-mRNA splicing factor [ Rattus norvegicus (Norway rat) ]

Gene ID: 312251, updated on 5-Jan-2022

Summary

Official Symbol
Luc7l2provided by RGD
Official Full Name
LUC7-like 2 pre-mRNA splicing factorprovided by RGD
Primary source
RGD:1308651
See related
Ensembl:ENSRNOG00000006001
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable enzyme binding activity and mRNA binding activity. Predicted to be involved in mRNA splice site selection. Predicted to be located in nuclear speck. Predicted to be part of U1 snRNP and U2-type prespliceosome. Orthologous to human LUC7L2 (LUC7 like 2, pre-mRNA splicing factor). [provided by Alliance of Genome Resources, Nov 2021]
Expression
Biased expression in Thymus (RPKM 214.6), Adrenal (RPKM 188.4) and 9 other tissues See more
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Genomic context

See Luc7l2 in Genome Data Viewer
Location:
4q22
Exon count:
15
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (67287593..67347986)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (66290319..66357970)

Chromosome 4 - NC_051339.1Genomic Context describing neighboring genes Neighboring gene transfer RNA arginine (anticodon CCU) Neighboring gene formation of mitochondrial complex V assembly factor 1 Neighboring gene small nuclear ribonucleoprotein E-like Neighboring gene insulin-induced gene 1 protein-like Neighboring gene killer cell lectin like receptor G2 Neighboring gene C-type lectin domain family 2, member L

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables enzyme binding ISO
Inferred from Sequence Orthology
more info
 
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in mRNA splice site selection IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
part_of U1 snRNP IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of U2-type prespliceosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nuclear speck ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
LUC7-like 2 pre-mRNA splicing factor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107853.1NP_001101323.1  LUC7-like 2 pre-mRNA splicing factor

    See identical proteins and their annotated locations for NP_001101323.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473959
    UniProtKB/TrEMBL
    B2RYP6
    Conserved Domains (1) summary
    pfam03194
    Location:5241
    LUC7; LUC7 N_terminus

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051339.1 Reference mRatBN7.2 Primary Assembly

    Range
    67287593..67347986
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006236314.4XP_006236376.1  LUC7-like 2 pre-mRNA splicing factor isoform X2

    See identical proteins and their annotated locations for XP_006236376.1

    Conserved Domains (1) summary
    pfam03194
    Location:41245
    LUC7; LUC7 N_terminus
  2. XM_006236316.4XP_006236378.1  LUC7-like 2 pre-mRNA splicing factor isoform X3

    See identical proteins and their annotated locations for XP_006236378.1

    Conserved Domains (1) summary
    pfam03194
    Location:26240
    LUC7; LUC7 N_terminus
  3. XM_006236321.3XP_006236383.1  LUC7-like 2 pre-mRNA splicing factor isoform X4

    See identical proteins and their annotated locations for XP_006236383.1

    Related
    ENSRNOP00000086709.1, ENSRNOT00000096758.1
    Conserved Domains (1) summary
    pfam03194
    Location:5241
    LUC7; LUC7 N_terminus
  4. XM_006236323.3XP_006236385.1  LUC7-like 2 pre-mRNA splicing factor isoform X5

    See identical proteins and their annotated locations for XP_006236385.1

    Conserved Domains (1) summary
    pfam03194
    Location:1188
    LUC7; LUC7 N_terminus
  5. XM_006236322.4XP_006236384.1  LUC7-like 2 pre-mRNA splicing factor isoform X5

    See identical proteins and their annotated locations for XP_006236384.1

    Related
    ENSRNOP00000077278.1, ENSRNOT00000098573.1
    Conserved Domains (1) summary
    pfam03194
    Location:1188
    LUC7; LUC7 N_terminus
  6. XM_006236315.4XP_006236377.1  LUC7-like 2 pre-mRNA splicing factor isoform X3

    See identical proteins and their annotated locations for XP_006236377.1

    Related
    ENSRNOP00000008557.6, ENSRNOT00000008557.7
    Conserved Domains (1) summary
    pfam03194
    Location:26240
    LUC7; LUC7 N_terminus
  7. XM_039107522.1XP_038963450.1  LUC7-like 2 pre-mRNA splicing factor isoform X5

    Conserved Domains (1) summary
    pfam03194
    Location:1188
    LUC7; LUC7 N_terminus
  8. XM_039107521.1XP_038963449.1  LUC7-like 2 pre-mRNA splicing factor isoform X1

    Conserved Domains (1) summary
    pfam03194
    Location:26240
    LUC7; LUC7 N_terminus
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