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Kiaa1549 KIAA1549 homolog [ Rattus norvegicus (Norway rat) ]

Gene ID: 312246, updated on 5-Jul-2025
Official Symbol
Kiaa1549provided by RGD
Official Full Name
KIAA1549 homologprovided by RGD
Primary source
RGD:1306271
See related
Ensembl:ENSRNOG00000013729 AllianceGenome:RGD:1306271
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1306271
Summary
Predicted to be located in photoreceptor connecting cilium. Human ortholog(s) of this gene implicated in retinitis pigmentosa 86. Orthologous to human KIAA1549 (KIAA1549). [provided by Alliance of Genome Resources, Jul 2025]
Expression
Biased expression in Brain (RPKM 41.2), Kidney (RPKM 30.7) and 9 other tissues See more
Orthologs
human mouse all
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See Kiaa1549 in Genome Data Viewer
Location:
4q23
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (67807635..67935303, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (66840674..66968407, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (65834933..65962722, complement)

Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene high-mobility group box 1, pseudogene 18 Neighboring gene SVOP like Neighboring gene ATPase H+ transporting V0 subunit a4 Neighboring gene uncharacterized LOC134486756 Neighboring gene transmembrane protein 213 Neighboring gene ZC3HAV1 like Neighboring gene zinc finger CCCH-type containing, antiviral 1

Go to nucleotide: Graphics FASTA GenBank

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Related articles in PubMed

  1. Homozygous variants in KIAA1549, encoding a ciliary protein, are associated with autosomal recessive retinitis pigmentosa. de Bruijn SE, et al. J Med Genet, 2018 Oct. PMID 30120214

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RGD

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in photoreceptor connecting cilium IEA
Inferred from Electronic Annotation
more info
  
located_in photoreceptor connecting cilium ISO
Inferred from Sequence Orthology
more info
  
Preferred Names
UPF0606 protein KIAA1549 homolog

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086022.1 Reference GRCr8

    Range
    67807635..67935303 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063286936.1 → XP_063143006.1  UPF0606 protein KIAA1549 homolog isoform X4

    UniProtKB/TrEMBL
    D3Z9D0

  2. XM_063286933.1 → XP_063143003.1  UPF0606 protein KIAA1549 homolog isoform X2

    UniProtKB/TrEMBL
    D3Z9D0

  3. XM_063286934.1 → XP_063143004.1  UPF0606 protein KIAA1549 homolog isoform X3

    UniProtKB/TrEMBL
    D3Z9D0

  4. XM_231616.10 → XP_231616.5  UPF0606 protein KIAA1549 homolog isoform X1

    See identical proteins and their annotated locations for XP_231616.5

    UniProtKB/TrEMBL
    D3Z9D0
    Related
    ENSRNOP00000050121.7, ENSRNOT00000040391.7
    Conserved Domains (1) summary
    pfam12877
    Location:1023 → 1688
    DUF3827; Domain of unknown function (DUF3827)

  5. XM_063286937.1 → XP_063143007.1  UPF0606 protein KIAA1549 homolog isoform X5

    UniProtKB/TrEMBL
    D3Z9D0
    Related
    ENSRNOP00000112386.1, ENSRNOT00000139757.1
Nucleotide Protein Strain
Heading Accession and Version

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