U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

CG4313 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31169, updated on 6-Jul-2026
Official Symbol
CG4313provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0025632
Locus tag
Dmel_CG4313
See related
AllianceGenome:FB:FBgn0025632
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG 4313; Dmel\CG4313; Dmel_CG4313; EG:22E5.10
Summary
Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Is expressed in larval visceral muscle cell and organism. Orthologous to human GPR84 (G protein-coupled receptor 84) and MTNR1A (melatonin receptor 1A). [provided by Alliance of Genome Resources, Jul 2025]
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See CG4313 in Genome Data Viewer
Location:
2C7-2C8; 1-0.5 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (2041868..2055414)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (1935901..1949447)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene enhanced adult sensory threshold Neighboring gene alpha actinin Neighboring gene mir-4954 stem loop Neighboring gene ultraspiracle Neighboring gene uncharacterized protein Neighboring gene moody Neighboring gene antisense RNA:CR44896 Neighboring gene Salt-inducible kinase 2 Neighboring gene uncharacterized protein

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Investigation of Evolutionary History and Origin of the Tre1 Family Suggests a Role in Regulating Hemocytes Cells Infiltration of the Blood-Brain Barrier. Kubick N, et al. Insects, 2021 Sep 29. PMID 34680651, Free PMC Article
  2. A novel free fatty acid receptor agonist improving metabolic health in Drosophila models. Brunetti K, et al. Pharmacol Res, 2025 Jun. PMID 40348099
  3. moody encodes two GPCRs that regulate cocaine behaviors and blood-brain barrier permeability in Drosophila. Bainton RJ, et al. Cell, 2005 Oct 7. PMID 16213219
  4. Melatonin increases the regularity of cardiac rhythmicity in the Drosophila heart in both wild-type and strains bearing pathogenic mutations. VanKirk T, et al. J Comp Physiol B, 2017 Jan. PMID 27448293
  5. Tre1, a G protein-coupled receptor, directs transepithelial migration of Drosophila germ cells. Kunwar PS, et al. PLoS Biol, 2003 Dec. PMID 14691551, Free PMC Article

See all (42) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables G protein-coupled receptor activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
involved_in G protein-coupled receptor signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
uncharacterized protein
Names
CG4313-PC
CG4313-PD
CG4313-PE

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    2041868..2055414
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001297871.1 → NP_001284800.1  uncharacterized protein Dmel_CG4313, isoform E

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T9K8, X2JA83
    Conserved Domains (1) summary
    cl21561
    Location:248 → 315
    7tm_4; Olfactory receptor

  2. NM_001297870.1 → NP_001284799.1  uncharacterized protein Dmel_CG4313, isoform C

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T9K8, X2JA83
    Conserved Domains (1) summary
    cl21561
    Location:248 → 315
    7tm_4; Olfactory receptor

  3. NM_130615.3 → NP_569971.3  uncharacterized protein Dmel_CG4313, isoform D

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W533
    Conserved Domains (1) summary
    cd15210
    Location:78 → 505
    7tmA_GPR84-like; G protein-coupled receptor 84 and similar proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O77269 O77269
Q8T9K8 Q8T9K8
Q9W533 Q9W533

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools