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Pax1 paired box 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 311505, updated on 13-Aug-2019

Summary

Official Symbol
Pax1provided by RGD
Official Full Name
paired box 1provided by RGD
Primary source
RGD:1588548
See related
Ensembl:ENSRNOG00000024882
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Pax-1
Summary
member of the paired box homeotic gene family; mouse homolog exhibits transcriptional activity and its mutation causes undulating malformations in the murine vertebral column [RGD, Feb 2006]
Expression
Restricted expression toward (RPKM 54.5) See more
Orthologs

Genomic context

See Pax1 in Genome Data Viewer
Location:
3q41
Exon count:
9
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (141577124..141589849)
106 current Rn_Celera (GCF_000002265.2) 3 AC_000071.1 (133651867..133663861)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 3 NC_005102.3 (147995989..148008334)

Chromosome 3 - NC_005102.4Genomic Context describing neighboring genes Neighboring gene NK2 homeobox 2 Neighboring gene uncharacterized LOC108350489 Neighboring gene uncharacterized LOC108350490 Neighboring gene similar to Alpha-enolase (2-phospho-D-glycerate hydro-lyase) (Non-neural enolase) (NNE) (Enolase 1)

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
CD4-positive, alpha-beta T cell differentiation ISO
Inferred from Sequence Orthology
more info
PubMed 
CD8-positive, alpha-beta T cell differentiation ISO
Inferred from Sequence Orthology
more info
PubMed 
bone morphogenesis ISO
Inferred from Sequence Orthology
more info
PubMed 
cell proliferation ISO
Inferred from Sequence Orthology
more info
PubMed 
parathyroid gland development ISO
Inferred from Sequence Orthology
more info
PubMed 
pattern specification process ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
PubMed 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
sclerotome development ISO
Inferred from Sequence Orthology
more info
PubMed 
skeletal system development ISO
Inferred from Sequence Orthology
more info
PubMed 
somitogenesis ISO
Inferred from Sequence Orthology
more info
PubMed 
thymus development ISO
Inferred from Sequence Orthology
more info
PubMed 

General protein information

Preferred Names
paired box protein Pax-1
Names
Paired box homeotic gene 1
paired box gene 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107787.1NP_001101257.1  paired box protein Pax-1

    See identical proteins and their annotated locations for NP_001101257.1

    Status: PROVISIONAL

    Source sequence(s)
    CH474026
    UniProtKB/TrEMBL
    F1LT82
    Related
    ENSRNOP00000062281.2, ENSRNOT00000067983.1

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005102.4 Reference Rnor_6.0 Primary Assembly

    Range
    141577124..141589849
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006235152.3XP_006235214.2  paired box protein Pax-1 isoform X1

    Conserved Domains (1) summary
    cd00131
    Location:130257
    PAX; Paired Box domain
  2. XM_017591769.1XP_017447258.1  paired box protein Pax-1 isoform X1

    Conserved Domains (1) summary
    cd00131
    Location:130257
    PAX; Paired Box domain
  3. XM_017591770.1XP_017447259.1  paired box protein Pax-1 isoform X2

Alternate Rn_Celera

Genomic

  1. AC_000071.1 Alternate Rn_Celera

    Range
    133651867..133663861
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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