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Adh6 alcohol dehydrogenase 6 (class V) [ Rattus norvegicus (Norway rat) ]

Gene ID: 310903, updated on 21-Jul-2018

Summary

Official Symbol
Adh6provided by RGD
Official Full Name
alcohol dehydrogenase 6 (class V)provided by RGD
Primary source
RGD:1306313
See related
Ensembl:ENSRNOG00000012436
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Expression
Restricted expression toward (RPKM 567.1) See more

Genomic context

See Adh6 in Genome Data Viewer
Location:
2q44
Exon count:
11
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (243656568..243687857)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 2 NC_005101.3 (262193252..262224625)

Chromosome 2 - NC_005101.4Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103691717 Neighboring gene similar to Alcohol dehydrogenase 1A (Alcohol dehydrogenase alpha subunit) Neighboring gene uncharacterized LOC108350123 Neighboring gene uncharacterized LOC102556299 Neighboring gene alcohol dehydrogenase 4 (class II), pi polypeptide Neighboring gene alcohol dehydrogenase 5 (class III), chi polypeptide

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
alcohol dehydrogenase (NAD) activity IEA
Inferred from Electronic Annotation
more info
 
alcohol dehydrogenase (NAD) activity ISO
Inferred from Sequence Orthology
more info
 
alcohol dehydrogenase activity, zinc-dependent ISO
Inferred from Sequence Orthology
more info
 
molecular_function ND
No biological Data available
more info
 
oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
biological_process ND
No biological Data available
more info
 
ethanol oxidation ISO
Inferred from Sequence Orthology
more info
 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
response to ethanol ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cellular_component ND
No biological Data available
more info
 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
alcohol dehydrogenase 6
Names
class V alcohol dehydrogenase
NP_001012084.1
XP_006233434.1
XP_006233436.1
XP_006233439.1
XP_008759729.1
XP_017446428.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012084.1NP_001012084.1  alcohol dehydrogenase 6

    See identical proteins and their annotated locations for NP_001012084.1

    Status: PROVISIONAL

    Source sequence(s)
    BC083792
    UniProtKB/Swiss-Prot
    Q5XI95
    Related
    ENSRNOP00000030638.4, ENSRNOT00000036993.4
    Conserved Domains (2) summary
    cd08299
    Location:3376
    alcohol_DH_class_I_II_IV; class I, II, IV alcohol dehydrogenases
    COG1062
    Location:8374
    FrmA; Zn-dependent alcohol dehydrogenase [General function prediction only]

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005101.4 Reference Rnor_6.0 Primary Assembly

    Range
    243656568..243687857
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006233374.1XP_006233436.1  alcohol dehydrogenase 6 isoform X3

    See identical proteins and their annotated locations for XP_006233436.1

    Conserved Domains (2) summary
    cd08299
    Location:20389
    alcohol_DH_class_I_II_IV; class I, II, IV alcohol dehydrogenases
    COG1062
    Location:21387
    FrmA; Zn-dependent alcohol dehydrogenase [General function prediction only]
  2. XM_017590939.1XP_017446428.1  alcohol dehydrogenase 6 isoform X2

    Conserved Domains (2) summary
    cd08299
    Location:22392
    alcohol_DH_class_I_II_IV; class I, II, IV alcohol dehydrogenases
    COG1062
    Location:24390
    FrmA; Zn-dependent alcohol dehydrogenase [General function prediction only]
  3. XM_008761507.2XP_008759729.1  alcohol dehydrogenase 6 isoform X3

    See identical proteins and their annotated locations for XP_008759729.1

    Conserved Domains (2) summary
    cd08299
    Location:20389
    alcohol_DH_class_I_II_IV; class I, II, IV alcohol dehydrogenases
    COG1062
    Location:21387
    FrmA; Zn-dependent alcohol dehydrogenase [General function prediction only]
  4. XM_006233372.2XP_006233434.1  alcohol dehydrogenase 6 isoform X1

    Conserved Domains (2) summary
    cd08299
    Location:44413
    alcohol_DH_class_I_II_IV; class I, II, IV alcohol dehydrogenases
    COG1062
    Location:45411
    FrmA; Zn-dependent alcohol dehydrogenase [General function prediction only]
  5. XM_006233377.3XP_006233439.1  alcohol dehydrogenase 6 isoform X4

    See identical proteins and their annotated locations for XP_006233439.1

    Conserved Domains (2) summary
    COG1062
    Location:1334
    FrmA; Zn-dependent alcohol dehydrogenase [General function prediction only]
    cl16912
    Location:1336
    MDR; Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family

Alternate Rn_Celera

Genomic

  1. AC_000070.1 Alternate Rn_Celera

    Range
    219059887..219091198
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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