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Tmem185a transmembrane protein 185A [ Rattus norvegicus (Norway rat) ]

Gene ID: 309357, updated on 5-Mar-2024

Summary

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Official Symbol
Tmem185aprovided by RGD
Official Full Name
transmembrane protein 185Aprovided by RGD
Primary source
RGD:1563037
See related
Ensembl:ENSRNOG00000011047 AllianceGenome:RGD:1563037
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1563037
Summary
Predicted to be integral component of membrane. Predicted to be active in dendrite. Orthologous to human TMEM185A (transmembrane protein 185A). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 101.0), Lung (RPKM 84.5) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
Xq37
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (154187833..154212557)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (149143026..149167757)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (69568516..69593223, complement)

Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene DNA ligase 1-like Neighboring gene MAGE family member A13, pseudogene 2 Neighboring gene MAGE family member A13, pseudogene 1 Neighboring gene adenosylmethionine decarboxylase 1, pseudogene 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Cloning of a novel neuronally expressed orphan G-protein-coupled receptor which is up-regulated by erythropoietin, interacts with microtubule-associated protein 1b and colocalizes with the 5-hydroxytryptamine 2a receptor. Maurer MH, et al. J Neurochem, 2004 Nov. PMID 15525354
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Component Evidence Code Pubs
is_active_in dendrite IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in dendrite ISO
Inferred from Sequence Orthology
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
transmembrane protein 185A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001135712.2 → NP_001129184.1  transmembrane protein 185A

    See identical proteins and their annotated locations for NP_001129184.1

    Status: PROVISIONAL

    Source sequence(s)
    JACYVU010000488
    UniProtKB/TrEMBL
    A6KUA5, D3ZWX2
    Related
    ENSRNOP00000063850.1, ENSRNOT00000066919.2
    Conserved Domains (1) summary
    pfam10269
    Location:31 → 253
    Tmemb_185A; Transmembrane Fragile-X-F protein

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086039.1 Reference GRCr8

    Range
    154187833..154212557
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039099686.2 → XP_038955614.1  transmembrane protein 185A isoform X1

    UniProtKB/TrEMBL
    A0A8I6A7Y0, A6KUA5
    Related
    ENSRNOP00000089323.1
    Conserved Domains (1) summary
    pfam10269
    Location:31 → 225
    Tmemb_185A; Transmembrane Fragile-X-F protein

  2. XM_063279974.1 → XP_063136044.1  transmembrane protein 185A isoform X2

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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