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Tnpo1 transportin 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 309126, updated on 12-Aug-2018

Summary

Official Symbol
Tnpo1provided by RGD
Official Full Name
transportin 1provided by RGD
Primary source
RGD:1308372
See related
Ensembl:ENSRNOG00000014999
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Expression
Biased expression in Kidney (RPKM 275.3), Adrenal (RPKM 268.7) and 9 other tissues See more
Orthologs

Genomic context

See Tnpo1 in Genome Data Viewer
Location:
2q12
Exon count:
26
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (29056219..29126882, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 2 NC_005101.3 (48238550..48308427, complement)

Chromosome 2 - NC_005101.4Genomic Context describing neighboring genes Neighboring gene ralA-binding protein 1-like Neighboring gene hypothetical LOC100364548 Neighboring gene FCH domain only 2 Neighboring gene similar to HIStone family member (his-41) Neighboring gene zinc finger protein 366 Neighboring gene uncharacterized LOC108349928

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
Ran GTPase binding IEA
Inferred from Electronic Annotation
more info
 
nuclear localization sequence binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
NLS-bearing protein import into nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ribosomal protein import into nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
nuclear membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nuclear periphery IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001100692.1NP_001094162.1  transportin-1

    See identical proteins and their annotated locations for NP_001094162.1

    Status: VALIDATED

    Source sequence(s)
    AABR07007807, AABR07007809
    UniProtKB/TrEMBL
    F1LQP9
    Related
    ENSRNOP00000020543.7, ENSRNOT00000020543.7
    Conserved Domains (5) summary
    cd00020
    Location:127242
    ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
    pfam03810
    Location:34101
    IBN_N; Importin-beta N-terminal domain
    pfam13513
    Location:411465
    HEAT_EZ; HEAT-like repeat
    pfam13646
    Location:400503
    HEAT_2; HEAT repeats
    sd00044
    Location:95116
    HEAT; HEAT repeat [structural motif]

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005101.4 Reference Rnor_6.0 Primary Assembly

    Range
    29056219..29126882 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006231840.3XP_006231902.1  transportin-1 isoform X1

    See identical proteins and their annotated locations for XP_006231902.1

    UniProtKB/TrEMBL
    F1LQP9
    Conserved Domains (5) summary
    cd00020
    Location:127242
    ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
    pfam03810
    Location:34101
    IBN_N; Importin-beta N-terminal domain
    pfam13513
    Location:411465
    HEAT_EZ; HEAT-like repeat
    pfam13646
    Location:400503
    HEAT_2; HEAT repeats
    sd00044
    Location:95116
    HEAT; HEAT repeat [structural motif]
  2. XM_006231839.3XP_006231901.1  transportin-1 isoform X1

    See identical proteins and their annotated locations for XP_006231901.1

    UniProtKB/TrEMBL
    F1LQP9
    Conserved Domains (5) summary
    cd00020
    Location:127242
    ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
    pfam03810
    Location:34101
    IBN_N; Importin-beta N-terminal domain
    pfam13513
    Location:411465
    HEAT_EZ; HEAT-like repeat
    pfam13646
    Location:400503
    HEAT_2; HEAT repeats
    sd00044
    Location:95116
    HEAT; HEAT repeat [structural motif]
  3. XM_008760668.2XP_008758890.1  transportin-1 isoform X1

    See identical proteins and their annotated locations for XP_008758890.1

    UniProtKB/TrEMBL
    F1LQP9
    Conserved Domains (5) summary
    cd00020
    Location:127242
    ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
    pfam03810
    Location:34101
    IBN_N; Importin-beta N-terminal domain
    pfam13513
    Location:411465
    HEAT_EZ; HEAT-like repeat
    pfam13646
    Location:400503
    HEAT_2; HEAT repeats
    sd00044
    Location:95116
    HEAT; HEAT repeat [structural motif]

Alternate Rn_Celera

Genomic

  1. AC_000070.1 Alternate Rn_Celera

    Range
    26240332..26302645 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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