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Gatd1 glutamine amidotransferase class 1 domain containing 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 309110, updated on 8-Apr-2026
Official Symbol
Gatd1provided by RGD
Official Full Name
glutamine amidotransferase class 1 domain containing 1provided by RGD
Primary source
RGD:1304836
See related
Ensembl:ENSRNOG00000045795 AllianceGenome:RGD:1304836
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Pddc1; RGD1304836
Summary
Predicted to enable glyoxalase III activity. Predicted to be involved in methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione. Predicted to be located in early endosome and extracellular region. Predicted to be active in cytoplasm. Orthologous to human GATD1 (glutamine amidotransferase class 1 domain containing 1). [provided by Alliance of Genome Resources, Jul 2025]
Expression
Biased expression in Adrenal (RPKM 185.5), Kidney (RPKM 137.8) and 9 other tissues See more
Orthologs
all
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Try the new Transcripts and proteins table
See Gatd1 in Genome Data Viewer
Location:
1q41
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (205936189..205942121, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (196504533..196512561, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (214389006..214394451, complement)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene EPS8 signaling adaptor L2 Neighboring gene transaldolase 1 Neighboring gene solute carrier family 25 member 22 Neighboring gene cell cycle exit and neuronal differentiation 1 Neighboring gene p53-induced death domain protein 1

Go to nucleotide: Graphics FASTA GenBank

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Related articles in PubMed

  1. Large-scale proteomics and phosphoproteomics of urinary exosomes. Gonzales PA, et al. J Am Soc Nephrol, 2009 Feb. PMID 19056867, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables glyoxalase III activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in methylglyoxal catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in methylglyoxal catabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in early endosome IEA
Inferred from Electronic Annotation
more info
  
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
glutamine amidotransferase-like class 1 domain-containing protein 1
Names
Parkinson disease 7 domain containing 1
Parkinson disease 7 domain-containing protein 1
Parkinson disease 7 domain-containing protein 1-like
glutamine amidotransferase like class 1 domain containing 1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107563.2 → NP_001101033.1  glutamine amidotransferase-like class 1 domain-containing protein 1

    See identical proteins and their annotated locations for NP_001101033.1

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000001
    UniProtKB/TrEMBL
    A6HXV9, A6HXW0
    Conserved Domains (2) summary
    cd03141
    Location:12 → 216
    GATase1_Hsp31_like; Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Escherichia coli Hsp31 protein
    COG0693
    Location:31 → 204
    ThiJ; Putative intracellular protease/amidase [General function prediction only]

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    205936189..205942121 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017590251.3 → XP_017445740.2  glutamine amidotransferase-like class 1 domain-containing protein 1 isoform X1

    UniProtKB/TrEMBL
    D3ZVI9
    Related
    ENSRNOP00000065958.3, ENSRNOT00000073220.4
    Conserved Domains (1) summary
    cl00020
    Location:37 → 176
    GAT_1; Type 1 glutamine amidotransferase (GATase1)-like domain
Nucleotide Protein Strain
Heading Accession and Version

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