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Ovch2 ovochymase 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 308919, updated on 8-Apr-2026
Official Symbol
Ovch2provided by RGD
Official Full Name
ovochymase 2provided by RGD
Primary source
RGD:1564636
See related
Ensembl:ENSRNOG00000019794 AllianceGenome:RGD:1564636
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Ovch2-ps1; RGD1564636
Summary
Predicted to enable serine-type endopeptidase activity. Predicted to be involved in fertilization. Orthologous to human OVCH2 (ovochymase 2). [provided by Alliance of Genome Resources, Jul 2025]
Expression
Biased expression in Heart (RPKM 1.9), Muscle (RPKM 0.9) and 2 other tissues See more
Orthologs
all
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See Ovch2 in Genome Data Viewer
Location:
1q33
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (171105366..171125699, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (161693619..161713952, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (172009555..172030164, complement)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene PPFIB scaffold protein 2 Neighboring gene cytochrome b5 reductase 2 Neighboring gene carnitine deficiency-associated gene expressed in ventricle 3 like 1 Neighboring gene olfactory receptor family 8 subfamily I member 6, pseudogene 1 Neighboring gene olfactory receptor family 5 subfamily P member 5B

Go to nucleotide: Graphics FASTA GenBank

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables serine-type endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables serine-type endopeptidase activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in fertilization IEA
Inferred from Electronic Annotation
more info
  
involved_in fertilization ISO
Inferred from Sequence Orthology
more info
  
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
ovochymase-2
Names
ovochymase 2, pseudogene 1

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    171105366..171125699 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003748959.5 → XP_003749007.2  ovochymase-2

    UniProtKB/TrEMBL
    A6I7S7
    Related
    ENSRNOP00000026807.5, ENSRNOT00000026807.5
    Conserved Domains (2) summary
    cd00041
    Location:431 → 541
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cd00190
    Location:52 → 297
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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