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rnf141 ring finger protein 141 [ Rattus norvegicus (Norway rat) ]

Gene ID: 308900, updated on 3-Apr-2024

Summary

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Official Symbol
rnf141provided by RGD
Official Full Name
ring finger protein 141provided by RGD
Primary source
RGD:1303154
See related
AllianceGenome:RGD:1303154
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in protein autoubiquitination. Predicted to act upstream of or within regulation of transcription, DNA-templated. Predicted to be located in membrane. Orthologous to human RNF141 (ring finger protein 141). [provided by Alliance of Genome Resources, Apr 2022]
Annotation information
Annotation category: suggests misassembly
Expression
Biased expression in Liver (RPKM 244.9), Brain (RPKM 168.1) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
1q33
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (174365789..174391848, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (164933972..164957081, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (175631656..175657485, complement)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108349612 Neighboring gene uncharacterized LOC103691204 Neighboring gene adenosine monophosphate deaminase 3 Neighboring gene lymphatic vessel endothelial hyaluronan receptor 1 Neighboring gene inositol 1,4,5-triphosphate receptor associated 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. The zinc finger domain of RING finger protein 141 reveals a unique RING fold. Miyamoto K, et al. Protein Sci, 2017 Aug. PMID 28547869, Free PMC Article
  2. Molecular cloning and characterization of a mouse spermatogenesis-related ring finger gene znf230. Qiu W, et al. Biochem Biophys Res Commun, 2003 Jun 27. PMID 12804569
  3. Protein microarray characterization of the S-nitrosoproteome. Lee YI, et al. Mol Cell Proteomics, 2014 Jan. PMID 24105792, Free PMC Article
  4. Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. Na CH, et al. J Proteome Res, 2012 Sep 7. PMID 22871113, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables ubiquitin-protein transferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ubiquitin-protein transferase activity IEA
Inferred from Electronic Annotation
more info
  
enables ubiquitin-protein transferase activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in protein autoubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein autoubiquitination IEA
Inferred from Electronic Annotation
more info
  
involved_in protein autoubiquitination ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within regulation of DNA-templated transcription ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
RING finger protein 141

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001001800.1 → NP_001001800.1  RING finger protein 141

    See identical proteins and their annotated locations for NP_001001800.1

    Status: PROVISIONAL

    Source sequence(s)
    AY621087
    UniProtKB/Swiss-Prot
    Q6IV57
    UniProtKB/TrEMBL
    A6I825
    Conserved Domains (2) summary
    TIGR00599
    Location:129 → 207
    rad18; DNA repair protein rad18
    cd16545
    Location:154 → 192
    RING-HC_RNF141; RING finger, HC subclass, found in RING finger protein 141 (RNF141) and similar proteins

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    174365789..174391848 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063262931.1 → XP_063119001.1  RING finger protein 141 isoform X1

    UniProtKB/Swiss-Prot
    Q6IV57
    UniProtKB/TrEMBL
    A6I825

  2. XM_063262934.1 → XP_063119004.1  RING finger protein 141 isoform X2

  3. XM_063262938.1 → XP_063119008.1  RING finger protein 141 isoform X4

  4. XM_063262937.1 → XP_063119007.1  RING finger protein 141 isoform X3

RNA

  1. XR_010052932.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6IV57.1 GenPept UniProtKB/Swiss-Prot:Q6IV57

Gene LinkOut

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