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Tyr tyrosinase [ Rattus norvegicus (Norway rat) ]

Gene ID: 308800, updated on 2-Oct-2018

Summary

Symbol
Tyrprovided by RGD
Full Name
tyrosinaseprovided by RGD
Primary source
RGD:1589755
See related
Ensembl:ENSRNOG00000016421
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
C
Expression
Low expression observed in reference dataset See more
Orthologs

Genomic context

See Tyr in Genome Data Viewer
Location:
1q32
Exon count:
5
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (151012598..151106802, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 1 NC_005100.3 (157322968..157416594, complement)

Chromosome 1 - NC_005100.4Genomic Context describing neighboring genes Neighboring gene 40S ribosomal protein S4, X isoform-like Neighboring gene NADPH oxidase 4 Neighboring gene uncharacterized LOC103691187 Neighboring gene glutamate metabotropic receptor 5 Neighboring gene splicing factor 3A subunit 1-like Neighboring gene eukaryotic translation initiation factor 5-like

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
copper ion binding IEA
Inferred from Electronic Annotation
more info
 
copper ion binding ISO
Inferred from Sequence Orthology
more info
 
monophenol monooxygenase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
monophenol monooxygenase activity ISO
Inferred from Sequence Orthology
more info
 
protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
 
protein heterodimerization activity ISO
Inferred from Sequence Orthology
more info
 
protein homodimerization activity IEA
Inferred from Electronic Annotation
more info
 
protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
cell proliferation IEA
Inferred from Electronic Annotation
more info
 
cell proliferation ISO
Inferred from Sequence Orthology
more info
 
melanin biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
melanin biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
pigmentation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
pigmentation IMP
Inferred from Mutant Phenotype
more info
PubMed 
pigmentation ISO
Inferred from Sequence Orthology
more info
 
response to UV IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
response to UV IEP
Inferred from Expression Pattern
more info
PubMed 
response to cAMP IEP
Inferred from Expression Pattern
more info
PubMed 
response to vitamin D IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
response to vitamin D IEP
Inferred from Expression Pattern
more info
PubMed 
thymus development IEA
Inferred from Electronic Annotation
more info
 
thymus development ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cellular_component ND
No biological Data available
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
colocalizes_with melanosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
melanosome ISO
Inferred from Sequence Orthology
more info
 
colocalizes_with melanosome ISO
Inferred from Sequence Orthology
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
 
perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107535.1NP_001101005.1  tyrosinase precursor

    See identical proteins and their annotated locations for NP_001101005.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473956
    UniProtKB/TrEMBL
    D4A9G4
    Related
    ENSRNOP00000021971.4, ENSRNOT00000021971.4
    Conserved Domains (1) summary
    pfam00264
    Location:171403
    Tyrosinase; Common central domain of tyrosinase

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005100.4 Reference Rnor_6.0 Primary Assembly

    Range
    151012598..151106802 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera

Genomic

  1. AC_000069.1 Alternate Rn_Celera

    Range
    139445261..139532999 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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