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Ddx18 DEAD-box helicase 18 [ Rattus norvegicus (Norway rat) ]

Gene ID: 308490, updated on 2-Oct-2018

Summary

Official Symbol
Ddx18provided by RGD
Official Full Name
DEAD-box helicase 18provided by RGD
Primary source
RGD:1549712
See related
Ensembl:ENSRNOG00000025430
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
MrDb
Expression
Biased expression in Thymus (RPKM 162.4), Spleen (RPKM 130.9) and 9 other tissues See more
Orthologs

Genomic context

See Ddx18 in Genome Data Viewer
Location:
13q11
Exon count:
13
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (37522558..37536066, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 13 NC_005112.3 (42680394..42693902, complement)

Chromosome 13 - NC_005112.4Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 93 Neighboring gene 5-hydroxytryptamine (serotonin) receptor 5B Neighboring gene heterogeneous nuclear ribonucleoprotein A3-like Neighboring gene developmental pluripotency-associated protein 2 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Homology

Clone Names

  • MGC95311

Gene Ontology Provided by RGD

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
RNA binding IEA
Inferred from Electronic Annotation
more info
 
helicase activity IEA
Inferred from Electronic Annotation
more info
 
molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
cellular response to estradiol stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
Component Evidence Code Pubs
cellular_component ND
No biological Data available
more info
 
chromosome IEA
Inferred from Electronic Annotation
more info
 
chromosome ISO
Inferred from Sequence Orthology
more info
 
nucleolus IEA
Inferred from Electronic Annotation
more info
 
nucleolus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
ATP-dependent RNA helicase DDX18
Names
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
Myc-regulated DEAD box protein
NP_001006997.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001006996.1NP_001006997.1  ATP-dependent RNA helicase DDX18

    See identical proteins and their annotated locations for NP_001006997.1

    Status: PROVISIONAL

    Source sequence(s)
    BC083919
    UniProtKB/TrEMBL
    Q5XHY0
    Related
    ENSRNOP00000038728.3, ENSRNOT00000037203.3
    Conserved Domains (4) summary
    smart00487
    Location:198386
    DEXDc; DEAD-like helicases superfamily
    cd00079
    Location:404533
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    cd00268
    Location:183390
    DEADc; DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif ...
    pfam13959
    Location:565623
    DUF4217; Domain of unknown function (DUF4217)

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005112.4 Reference Rnor_6.0 Primary Assembly

    Range
    37522558..37536066 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera

Genomic

  1. AC_000081.1 Alternate Rn_Celera

    Range
    32594103..32607613 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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