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Kifc3 kinesin family member C3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 307644, updated on 30-Sep-2021

Summary

Official Symbol
Kifc3provided by RGD
Official Full Name
kinesin family member C3provided by RGD
Primary source
RGD:1307693
See related
EnsemblRapid:ENSRNOG00000014087
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
KRP4
Expression
Biased expression in Kidney (RPKM 88.0), Adrenal (RPKM 44.9) and 9 other tissues See more
Orthologs
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Genomic context

See Kifc3 in Genome Data Viewer
Location:
19p13
Exon count:
29
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (9825208..9920371)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (10305405..10339186)

Chromosome 19 - NC_051354.1Genomic Context describing neighboring genes Neighboring gene cyclic nucleotide gated channel subunit beta 1 Neighboring gene U2 spliceosomal RNA Neighboring gene katanin regulatory subunit B1 Neighboring gene dynein regulatory complex subunit 7

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Homology

Clone Names

  • MGC156699

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
enables microtubule binding IEA
Inferred from Electronic Annotation
more info
 
enables minus-end-directed microtubule motor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within Golgi organization ISO
Inferred from Sequence Orthology
more info
 
involved_in epithelial cell-cell adhesion ISO
Inferred from Sequence Orthology
more info
 
involved_in microtubule-based movement IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within microtubule-based process ISO
Inferred from Sequence Orthology
more info
 
involved_in zonula adherens maintenance ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
located_in centrosome ISO
Inferred from Sequence Orthology
more info
 
part_of kinesin complex ISO
Inferred from Sequence Orthology
more info
 
located_in microtubule IEA
Inferred from Electronic Annotation
more info
 
located_in zonula adherens ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001103352.1NP_001096822.1  kinesin-like protein KIFC3

    See identical proteins and their annotated locations for NP_001096822.1

    Status: PROVISIONAL

    Source sequence(s)
    BC128748
    UniProtKB/TrEMBL
    A1A5P4
    Related
    ENSRNOP00000085654.1, ENSRNOT00000093890.1
    Conserved Domains (3) summary
    cd01366
    Location:370697
    KISc_C_terminal; Kinesin motor domain, KIFC2/KIFC3/ncd-like carboxy-terminal kinesins
    pfam00225
    Location:378695
    Kinesin; Kinesin motor domain
    cl12013
    Location:108233
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051354.1 Reference mRatBN7.2 Primary Assembly

    Range
    9825208..9920371
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017601266.2XP_017456755.2  kinesin-like protein KIFC3 isoform X3

    Conserved Domains (2) summary
    COG1196
    Location:231548
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd01366
    Location:598925
    KISc_C_terminal; Kinesin motor domain, KIFC2/KIFC3/ncd-like carboxy-terminal kinesins
  2. XM_039097698.1XP_038953626.1  kinesin-like protein KIFC3 isoform X1

    Conserved Domains (2) summary
    COG1196
    Location:231548
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd01366
    Location:598925
    KISc_C_terminal; Kinesin motor domain, KIFC2/KIFC3/ncd-like carboxy-terminal kinesins
  3. XM_017601269.2XP_017456758.2  kinesin-like protein KIFC3 isoform X6

    Related
    ENSRNOP00000092397.1, ENSRNOT00000095742.1
    Conserved Domains (2) summary
    COG1196
    Location:231548
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd01366
    Location:598925
    KISc_C_terminal; Kinesin motor domain, KIFC2/KIFC3/ncd-like carboxy-terminal kinesins
  4. XM_017601267.2XP_017456756.2  kinesin-like protein KIFC3 isoform X4

    Conserved Domains (2) summary
    COG1196
    Location:231548
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd01366
    Location:598925
    KISc_C_terminal; Kinesin motor domain, KIFC2/KIFC3/ncd-like carboxy-terminal kinesins
  5. XM_017601265.2XP_017456754.2  kinesin-like protein KIFC3 isoform X2

    Conserved Domains (2) summary
    COG1196
    Location:230547
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd01366
    Location:597924
    KISc_C_terminal; Kinesin motor domain, KIFC2/KIFC3/ncd-like carboxy-terminal kinesins
  6. XM_039097699.1XP_038953627.1  kinesin-like protein KIFC3 isoform X7

    Conserved Domains (2) summary
    TIGR02168
    Location:179488
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd01366
    Location:491818
    KISc_C_terminal; Kinesin motor domain, KIFC2/KIFC3/ncd-like carboxy-terminal kinesins
  7. XM_017601270.2XP_017456759.2  kinesin-like protein KIFC3 isoform X8

    Conserved Domains (2) summary
    TIGR02168
    Location:179488
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd01366
    Location:491818
    KISc_C_terminal; Kinesin motor domain, KIFC2/KIFC3/ncd-like carboxy-terminal kinesins
  8. XM_008772288.3XP_008770510.2  kinesin-like protein KIFC3 isoform X5

    Conserved Domains (2) summary
    COG1196
    Location:181498
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd01366
    Location:548875
    KISc_C_terminal; Kinesin motor domain, KIFC2/KIFC3/ncd-like carboxy-terminal kinesins
  9. XM_008772295.3XP_008770517.2  kinesin-like protein KIFC3 isoform X12

    Related
    ENSRNOP00000058969.2, ENSRNOT00000066032.3
    Conserved Domains (2) summary
    TIGR02168
    Location:129438
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd01366
    Location:441768
    KISc_C_terminal; Kinesin motor domain, KIFC2/KIFC3/ncd-like carboxy-terminal kinesins
  10. XM_039097702.1XP_038953630.1  kinesin-like protein KIFC3 isoform X10

    Conserved Domains (2) summary
    TIGR02168
    Location:58367
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd01366
    Location:370697
    KISc_C_terminal; Kinesin motor domain, KIFC2/KIFC3/ncd-like carboxy-terminal kinesins
  11. XM_039097701.1XP_038953629.1  kinesin-like protein KIFC3 isoform X9

    Conserved Domains (3) summary
    TIGR02168
    Location:93402
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd01366
    Location:405732
    KISc_C_terminal; Kinesin motor domain, KIFC2/KIFC3/ncd-like carboxy-terminal kinesins
    pfam08317
    Location:26150
    Spc7; Spc7 kinetochore protein
  12. XM_039097700.1XP_038953628.1  kinesin-like protein KIFC3 isoform X9

    Related
    ENSRNOP00000080196.1, ENSRNOT00000104498.1
    Conserved Domains (3) summary
    TIGR02168
    Location:93402
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd01366
    Location:405732
    KISc_C_terminal; Kinesin motor domain, KIFC2/KIFC3/ncd-like carboxy-terminal kinesins
    pfam08317
    Location:26150
    Spc7; Spc7 kinetochore protein
  13. XM_008772292.3XP_008770514.2  kinesin-like protein KIFC3 isoform X10

    Conserved Domains (2) summary
    TIGR02168
    Location:58367
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd01366
    Location:370697
    KISc_C_terminal; Kinesin motor domain, KIFC2/KIFC3/ncd-like carboxy-terminal kinesins
  14. XM_008772296.3XP_008770518.2  kinesin-like protein KIFC3 isoform X13

    Conserved Domains (2) summary
    TIGR02168
    Location:3301
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd01366
    Location:304631
    KISc_C_terminal; Kinesin motor domain, KIFC2/KIFC3/ncd-like carboxy-terminal kinesins
  15. XM_008772294.3XP_008770516.2  kinesin-like protein KIFC3 isoform X11

    Conserved Domains (2) summary
    TIGR02168
    Location:49358
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd01366
    Location:361688
    KISc_C_terminal; Kinesin motor domain, KIFC2/KIFC3/ncd-like carboxy-terminal kinesins
  16. XM_008772293.2XP_008770515.2  kinesin-like protein KIFC3 isoform X11

    Related
    ENSRNOP00000094247.1, ENSRNOT00000107028.1
    Conserved Domains (2) summary
    TIGR02168
    Location:49358
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd01366
    Location:361688
    KISc_C_terminal; Kinesin motor domain, KIFC2/KIFC3/ncd-like carboxy-terminal kinesins

RNA

  1. XR_005496646.1 RNA Sequence

  2. XR_005496647.1 RNA Sequence

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