Timm21 translocase of inner mitochondrial membrane 21 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Timm21provided by RGD
Official Full Name: translocase of inner mitochondrial membrane 21provided by RGD
Primary source: RGD:1307279
See related: Ensembl:ENSRNOG00000015142 AllianceGenome:RGD:1307279
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1307279
Summary: Predicted to be involved in mitochondrial cytochrome c oxidase assembly; mitochondrial respiratory chain complex I assembly; and protein import into mitochondrial matrix. Predicted to be located in mitochondrion. Predicted to be part of TIM23 mitochondrial import inner membrane translocase complex. Orthologous to human TIMM21 (translocase of inner mitochondrial membrane 21). [provided by Alliance of Genome Resources, Apr 2025]
Expression: Biased expression in Heart (RPKM 421.5), Muscle (RPKM 284.7) and 9 other tissues See more
Orthologs: all
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Genomic context

Location:: 18q12.3

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	18	NC_086036.1 (80589775..80594237, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	18	NC_051353.1 (78314900..78319362, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	18	NC_005117.4 (81803165..81807627, complement)

Chromosome 18 - NC_086036.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
involved_in mitochondrial respiratory chain complex I assembly	IEA Inferred from Electronic Annotation more info
involved_in mitochondrial respiratory chain complex I assembly	ISO Inferred from Sequence Orthology more info
involved_in mitochondrial respiratory chain complex I assembly	ISS Inferred from Sequence or Structural Similarity more info
involved_in mitochondrial respiratory chain complex IV assembly	IEA Inferred from Electronic Annotation more info
involved_in mitochondrial respiratory chain complex IV assembly	ISO Inferred from Sequence Orthology more info
involved_in mitochondrial respiratory chain complex IV assembly	ISS Inferred from Sequence or Structural Similarity more info
involved_in protein import into mitochondrial matrix	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein import into mitochondrial matrix	IEA Inferred from Electronic Annotation more info
involved_in protein import into mitochondrial matrix	ISO Inferred from Sequence Orthology more info
involved_in protein import into mitochondrial matrix	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
part_of TIM23 mitochondrial import inner membrane translocase complex	IBA Inferred from Biological aspect of Ancestor more info
part_of TIM23 mitochondrial import inner membrane translocase complex	IEA Inferred from Electronic Annotation more info
part_of TIM23 mitochondrial import inner membrane translocase complex	ISO Inferred from Sequence Orthology more info
part_of TIM23 mitochondrial import inner membrane translocase complex	ISS Inferred from Sequence or Structural Similarity more info
located_in mitochondrial membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: mitochondrial import inner membrane translocase subunit Tim21

Names: TIM21-like protein, mitochondrial; translocase of inner mitochondrial membrane 21 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.