Format

Send to:

Choose Destination

Nebl nebulette [ Rattus norvegicus (Norway rat) ]

Gene ID: 307189, updated on 18-Nov-2018

Summary

Official Symbol
Neblprovided by RGD
Official Full Name
nebuletteprovided by RGD
Primary source
RGD:1308315
See related
Ensembl:ENSRNOG00000049452
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Lasp-2
Expression
Biased expression in Heart (RPKM 1121.0), Lung (RPKM 134.5) and 1 other tissue See more
Orthologs

Genomic context

See Nebl in Genome Data Viewer
Location:
17q12.3
Exon count:
28
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (84141014..84247038, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 17 NC_005116.3 (85874473..85979946, complement)

Chromosome 17 - NC_005116.4Genomic Context describing neighboring genes Neighboring gene plexin domain containing 2 Neighboring gene uncharacterized LOC103694138 Neighboring gene hypothetical protein LOC680696 Neighboring gene uncharacterized LOC108348595 Neighboring gene uncharacterized LOC102553115

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
actin filament binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
actin filament binding ISO
Inferred from Sequence Orthology
more info
 
cytoskeletal protein binding ISO
Inferred from Sequence Orthology
more info
 
cytoskeletal protein binding ISS
Inferred from Sequence or Structural Similarity
more info
 
filamin binding IEA
Inferred from Electronic Annotation
more info
 
filamin binding ISO
Inferred from Sequence Orthology
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
tropomyosin binding IEA
Inferred from Electronic Annotation
more info
 
tropomyosin binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
cardiac muscle thin filament assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cardiac muscle thin filament assembly ISO
Inferred from Sequence Orthology
more info
 
cardiac muscle thin filament assembly ISS
Inferred from Sequence or Structural Similarity
more info
 
muscle fiber development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
Z disc IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Z disc ISO
Inferred from Sequence Orthology
more info
 
Z disc ISS
Inferred from Sequence or Structural Similarity
more info
 
stress fiber ISO
Inferred from Sequence Orthology
more info
 
stress fiber ISS
Inferred from Sequence or Structural Similarity
more info
 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001191694.1NP_001178623.1  nebulette

    Status: PROVISIONAL

    Source sequence(s)
    AABR07028742
    UniProtKB/TrEMBL
    D4A164
    Related
    ENSRNOP00000061086.2, ENSRNOT00000068553.3
    Conserved Domains (3) summary
    smart00227
    Location:462491
    NEBU; The Nebulin repeat is present also in Las1
    cd11935
    Location:9581015
    SH3_Nebulette_C; C-terminal Src Homology 3 domain of Nebulette and LIM-nebulette (or Lasp2)
    pfam00880
    Location:321347
    Nebulin; Nebulin repeat

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005116.4 Reference Rnor_6.0 Primary Assembly

    Range
    84141014..84247038 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera

Genomic

  1. AC_000085.1 Alternate Rn_Celera

    Range
    79405191..79510565 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center