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Odad2 outer dynein arm docking complex subunit 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 307036, updated on 5-Feb-2026
Official Symbol
Odad2provided by RGD
Official Full Name
outer dynein arm docking complex subunit 2provided by RGD
Primary source
RGD:1306933
See related
Ensembl:ENSRNOG00000018905 AllianceGenome:RGD:1306933
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Armc4; ddx5-ps1
Summary
Predicted to act upstream of or within several processes, including outer dynein arm assembly; regulation of cilium beat frequency; and ventricular system development. Predicted to be located in axoneme and ciliary base. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 23. Orthologous to human ODAD2 (outer dynein arm docking complex subunit 2). [provided by Alliance of Genome Resources, Jul 2025]
Expression
Biased expression in Testes (RPKM 62.1) and Lung (RPKM 14.1) See more
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See Odad2 in Genome Data Viewer
Location:
17q12.1
Exon count:
23
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (59910665..60104929, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (55216877..55409872, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (60283926..60474289)

Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene RAB18, member RAS oncogene family Neighboring gene mohawk homeobox Neighboring gene DEAD-box helicase 5, pseudogene 1 Neighboring gene proteasome activator subunit 1 like 1 Neighboring gene U2 spliceosomal RNA Neighboring gene MAGUK p55 scaffold protein 7

Go to nucleotide: Graphics FASTA GenBank

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Related articles in PubMed

  1. Combined exome and whole-genome sequencing identifies mutations in ARMC4 as a cause of primary ciliary dyskinesia with defects in the outer dynein arm. Onoufriadis A, et al. J Med Genet, 2014 Jan. PMID 24203976, Free PMC Article
  2. ARMC4 mutations cause primary ciliary dyskinesia with randomization of left/right body asymmetry. Hjeij R, et al. Am J Hum Genet, 2013 Aug 8. PMID 23849778, Free PMC Article
  3. Global genetic analysis in mice unveils central role for cilia in congenital heart disease. Li Y, et al. Nature, 2015 May 28. PMID 25807483, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in cilium movement IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within cilium movement ISO
Inferred from Sequence Orthology
more info
  
involved_in determination of left/right symmetry IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within determination of left/right symmetry ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within heart development ISO
Inferred from Sequence Orthology
more info
  
involved_in outer dynein arm assembly IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within outer dynein arm assembly ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within regulation of cilium beat frequency ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within ventricular system development ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in axoneme IEA
Inferred from Electronic Annotation
more info
  
located_in axoneme ISO
Inferred from Sequence Orthology
more info
  
located_in ciliary base ISO
Inferred from Sequence Orthology
more info
  
Preferred Names
outer dynein arm-docking complex subunit 2
Names
armadillo repeat containing 4
armadillo repeat-containing protein 4
ddx5-ps1 pseudogene

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001427763.1 → NP_001414692.1  outer dynein arm-docking complex subunit 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000017
    UniProtKB/TrEMBL
    A6KPM4

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086035.1 Reference GRCr8

    Range
    59910665..60104929 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039096476.2 → XP_038952404.1  outer dynein arm-docking complex subunit 2 isoform X3

    UniProtKB/TrEMBL
    A6KPM4
    Conserved Domains (3) summary
    COG5064
    Location:705 → 990
    SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
    sd00044
    Location:874 → 902
    HEAT; HEAT repeat [structural motif]
    sd00043
    Location:831 → 856
    ARM; armadillo repeat [structural motif]

  2. XM_039096475.2 → XP_038952403.1  outer dynein arm-docking complex subunit 2 isoform X1

    UniProtKB/TrEMBL
    A6KPM4, D3ZXG2
    Related
    ENSRNOP00000025585.7, ENSRNOT00000025585.8
    Conserved Domains (4) summary
    PLN03200
    Location:599 → 891
    PLN03200; cellulose synthase-interactive protein; Provisional
    COG5064
    Location:786 → 1071
    SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
    sd00044
    Location:955 → 983
    HEAT; HEAT repeat [structural motif]
    sd00043
    Location:912 → 937
    ARM; armadillo repeat [structural motif]

  3. XM_039096478.2 → XP_038952406.1  outer dynein arm-docking complex subunit 2 isoform X5

    Conserved Domains (3) summary
    PLN03200
    Location:256 → 548
    PLN03200; cellulose synthase-interactive protein; Provisional
    COG5064
    Location:443 → 728
    SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
    sd00043
    Location:603 → 632
    ARM; armadillo repeat [structural motif]

  4. XM_063276478.1 → XP_063132548.1  outer dynein arm-docking complex subunit 2 isoform X2

  5. XM_063276479.1 → XP_063132549.1  outer dynein arm-docking complex subunit 2 isoform X4

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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